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Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease. ....

United States , Qian Shi , Emily Henderson , Department Of Cellular , Ut Health San Antonio , Teresa Lozano Long School Of Medicine , Texas Health Science Center , San Antonio , Integrative Physiology , Teresa Lozano Long School , Lzheimer 39s Disease , Amyloid Plaque , Ouse Model ,

A review on the hallmarks of cancer and aging

Dr. Mikhail Blagosklonny published his new review paper in Aging (Aging-US) Volume 14, Issue 9, entitled, "Hallmarks of cancer and hallmarks of aging." ....

Mikhail Blagosklonny , Emily Henderson ,

Potential new therapeutic target for pancreatic cancer discovered

Northwestern Medicine investigators have discovered that targeting the G alpha 13 protein in pancreatic tumors promotes tumor growth and progression, according to a study published in Cell Reports. ....

Hidayatullahg Munshi , Emily Henderson , Division Of Hematology , Lora Lurie Professor , Pancreatic Cancer , Cell Signaling , Egg Protein , N Vitro , Ignaling Pathway ,

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19. ....

Diabetes Research , Clinical Practice , Middle Eastern Respiratory Syndrome Coronavirus , Coronavirus Disease Covid 19 , Ars Cov 2 , Cell Cycle , Immune System , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Intervention during the first five weeks of life prevents autism symptoms from ever developing in mice

Timing is key when treating developmental disorders. Blocking an overactive signaling pathway during the first five weeks of life prevents autism symptoms from ever developing in mice, according to new research published in JNeurosci. ....

Emily Henderson , Tuberous Sclerosis Complex , Ignaling Pathway ,