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Newly characterized stem cell self-renewal factor enables continuous sperm production

Unlike women, who are born with all the eggs they'll ever have, men can continue to produce sperm throughout their adult lives. To do so, they require a constant renewal of spermatogonial stem cells, which give rise to sperm. ....

Jeremy Wang , Ralphl Brinster , Emily Henderson , University Of Pennsylvania School Veterinary Medicine , Pennsylvania School , Veterinary Medicine , Distinguished Professor , Penn Vet , Somatic Cells , Stem Cells , Transcription Factors ,

Frozen testicular tissue can still make viable sperm 20 years later

Frozen testicular tissue is still viable after 20 years, according to a new study that holds implications for survivors of childhood cancer. ....

Robertj Kleberg Jr , Eoinc Whelan , Ralphl Brinster , University Of Pennsylvania , Helenc Kleberg Foundation ,