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Frequent testing improves the detection of SARS-CoV-2


Frequent testing improves the detection of SARS-CoV-2
Detecting SARS-CoV-2, the virus that causes COVID-19, improves with regularity of testing, whether using rapid antigen tests or PCR molecular tests. The PCR test is considered the gold standard for diagnosing COVID-19 infection, but cost and infrastructure issues, as well as wait times for PCR results, have limited its use more broadly as a screening tool for asymptomatic people because rapid results are needed to interrupt the chain of transmission.
In a highly anticipated study that compares rapid antigen and laboratory PCR approaches for COVID-19 serial screening, researchers affiliated with the National Institutes of Health s Rapid Acceleration of Diagnostics (RADx) initiative reported results from 43 people infected with the virus. They found that both testing methods were equally effective in detecting SARS-CoV-2 infection when tests were given on a regular cadence every three days. ....

United States , University Of Illinois , Bruce Tromberg , Abbott Alinity , William Heetderks , Christopherb Brooke , Johns Hopkins , Emily Henderson , Johns Hopkins University , University Of Massachusetts Medical School , Johns Hopkins School Of Medicine , National Institues , University Of Illinois At Urbana Champaign , National Institute Of Biomedical Imaging , National Institutes , Rapid Acceleration , National Institute , Biomedical Imaging , Infectious Diseases , Massachusetts Medical School , Johns Hopkins School , Quidel Sofia , Fluorescent Immunoassay , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் , ஜான்ஸ் ஹாப்கின்ஸ் ,

Lab reports 1st instance of SARS-CoV-2 variants affecting antigen test performance


Lab reports 1st instance of SARS-CoV-2 variants affecting antigen test performance
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has entered the second year and is marked by the emergence of several new and more infectious variant lineages. Many of these variants are also associated with immune escape.
The mutations in these variants are usually in the spike protein, which evolves rapidly in coronaviruses because of the continual need to escape humoral immunity. The evolution of the virus has affected many aspects of the COVID-19 pandemic, including mortality, therapeutic and vaccine efficacy, and diagnostic assay performance. While the viral evolution has impacted several FDA-authorized diagnostic tests, it has not affected the performance of antigen tests so far. ....

Abbott Binax , Susha Cheriyedath , Quidel Quickvue , Quidel Sofia ,