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New approach could treat infertility caused by abnormal GnRH secretion
Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism in the hypothalamus that controls the gonadotropin-releasing hormone (GnRH), which is a molecule that governs the reproductive function in men and women by regulating the release of a range of reproductive hormones into the body, particularly gonadotropins, from the pituitary gland, which is located underneath the brain.
In a healthy individual, GnRH and gonadotropins are released in pulses, while typically in individuals whose infertility is caused by hypothalmic dysfunction, the GnRH and gonadotropin pulses are supressed. ....

Japan General , Hiroko Tsukamura , Emily Henderson , Nagoya University , Proceedings Of The National Academy Sciences , School Of Bioagricultural Science , University Of Tokyo , National Institute , Physiological Sciences , Okazaki City , National Academy , Graduate School , Bioagricultural Science , Professor Hiroko Tsukamura , Kei Ichiro Maeda , Project Leader , Professor Uenoyama , Gene Therapy , Pituitary Gland , Reproductive Hormones , Viral Vector , ஜப்பான் ஜநரல் , எமிலி ஹென்டர்சன் , நாகோயா பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , தேசிய நிறுவனம் ,