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Novel genomic tools increase accuracy of breast cancer risk assessment
Findings from the FinnGen study encompassing 120,000 women indicate that inherited breast cancer risk should be assessed in an increasingly comprehensive manner. Currently, only individual gene mutations are taken into consideration in breast cancer therapy and prevention. The study demonstrates that more extensive genomic data can be used to identify women who are at high risk of breast cancer with considerably greater accuracy. Such knowledge can especially improve risk assessment among the close relatives of breast cancer patients.
In women, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related deaths. Genetic predisposition is one of the key risk factors associated with the disease. ....

Eteläuomen Läi , Jaakko Kaprio , Tuomo Meretoja , Mark Daly , Nina Mars , Samuli Ripatti , Aarno Palotie , Heikki Joensuu , Briotta Parolo , Nature Communications , University Of Helsinki , Molecular Medicine Finland , Professor Samuli Ripatti , Elisabeth Wid , Sini Kerminen , Matti Pirinen , Priit Palta , குறி டேலி , நினா செவ்வாய் கிரகம் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் ஹெல்சின்கி , மூலக்கூறு மருந்து பின்லாந்து ,