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Optimal timing of influenza vaccination in young children: population based cohort study

Objective To assess optimal timing of influenza vaccination in young children.

Design Population based cohort study.

Setting United States.

Participants Commercially insured children aged 2-5 years who were vaccinated against influenza during 2011-18.

Main outcome measure Rates of diagnosis of influenza among children who were vaccinated against influenza, by birth month.

Results Overall, 819 223 children aged 2-5 received influenza vaccination. Children vaccinated in November and December were least likely to have a diagnosis of influenza, a finding that may be confounded by unmeasured factors that influence the timing of vaccination and risk of influenza. Vaccination commonly occurred on days of preventive care visits and during birth months. Children born in October were disproportionately vaccinated in October and were, on average, vaccinated later than children born in August and earlier than those born in December. Children born in October had ....

United States , New York , Anupamb Jena , Christopherm Worsham , Charlesf Bray , Josephp Newhouse , New York Times , Alosa Health , Berkshire Hathaway Home Companies , Otsuka Pharmaceuticals , Edwards Life Sciences , Us Centers For Disease , Analysis Group , Tell Health , Precision Health Economics , Elixhauser Comorbidity Software , Sanofi Aventis , Vertex Pharmaceuticals , Marketscan Research Database , Disease Control , Current Procedural Terminology , Doubleday Books , Wall Street Journal , Open Access , Creative Commons Attribution Non Commercial ,

Patient mortality after surgery on the surgeon's birthday: observational study

Objective To determine whether patient mortality after surgery differs between surgeries performed on surgeons’ birthdays compared with other days of the year.

Design Retrospective observational study.

Setting US acute care and critical access hospitals.

Participants 100% fee-for-service Medicare beneficiaries aged 65 to 99 years who underwent one of 17 common emergency surgical procedures in 2011-14.

Main outcome measures Patient postoperative 30 day mortality, defined as death within 30 days after surgery, with adjustment for patient characteristics and surgeon fixed effects.

Results 980 876 procedures performed by 47 489 surgeons were analyzed. 2064 (0.2%) of the procedures were performed on surgeons’ birthdays. Patient characteristics, including severity of illness, were similar between patients who underwent surgery on a surgeon’s birthday and those who underwent surgery on other days. The overall unadjusted 30 day mortality on the oper ....

United Kingdom , United States , Yusuke Tsugawa , Charles Liu , Thomas Tsai , Ruthl Newhouse , Los Angeles , Ashishk Jha , Hirotaka Kato , Anupamb Jena , Eli Lilly , Rivfka Shenoy , Sanofi Aventis , National Institutes Of Health , University Of California , Bristol Myers Squibb , Precision Health Economics , Centers For Medicare Medicaid Service , Agency For Health Research , Hill Rom Services , Analysis Group , Vertex Pharmaceuticals , Among Medicare , Medicaid Service , Medicare Provider Enrollment , Ownership System ,