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Tackling the excesses of pharmaceutical marketing and promotion

Optimal timing of influenza vaccination in young children: population based cohort study

Objective To assess optimal timing of influenza vaccination in young children. Design Population based cohort study. Setting United States. Participants Commercially insured children aged 2-5 years who were vaccinated against influenza during 2011-18. Main outcome measure Rates of diagnosis of influenza among children who were vaccinated against influenza, by birth month. Results Overall, 819 223 children aged 2-5 received influenza vaccination. Children vaccinated in November and December were least likely to have a diagnosis of influenza, a finding that may be confounded by unmeasured factors that influence the timing of vaccination and risk of influenza. Vaccination commonly occurred on days of preventive care visits and during birth months. Children born in October were disproportionately vaccinated in October and were, on average, vaccinated later than children born in August and earlier than those born in December. Children born in October had the lowest rate of influenza

Comparative Safety of Two Opioid Treatments in Pregnancy Studied

Patents and regulatory exclusivities on FDA-approved insulin products: A longitudinal database study, 1986–2019

Anders Olsen and colleagues explore patenting on insulin products by the Federal Drug Agency (FDA) and the impact on market exclusivity and drug prices.

The Problem of Limited-Supply Agreements for Medicare Price Negotiation

This Viewpoint discusses how limited-supply agreements (introduction of generic products in reduced volumes) might thwart efforts to negotiate lower prices on p