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BBCNEWS BBC News October 21, 2021 16:47:00

They both have the genetic disease acute intermittent porphyria. potent opioid painkillers were a feature of their daily life, and liz was paralysed for two years. one of the times that they had to transfer me from one hospital to another because i wasn t breathing very well at all and i needed intensive care and mum was following behind in her car, following the ambulance. and as soon as the blue lights went on, shejust crumbled. i lost it all, it felt overnight. lost myjob, my company car, lost everything i d been working hard towards and in a new relationship not knowing whether my partner would stay with me. he did. we re married. we ve got a little girl now. but yeah, it was scary. gene silencing therapies get to the root cause of liz and sue s genetic disease rather than just managing their pain. they were part of trials here at king s college hospital, which showed the drug cut severe ....

Opioid Painkillers , Genetic Disease , College Hospital , Intensive Care , Lost Myjob , My Company Car , Gene Silencing , Sues Genetic , Root Cause , Little Girl ,

BBCNEWS BBC News October 21, 2021 19:45:00

Emma vardy, bbc news, armagh. the headlines on bbc news. borisjohnson has boris johnson has urged borisjohnson has urged people to get boosters as soon as they are able. 25 year old has been remanded in custody charged with the murder of sir david amess. he also faces charges for preparing acts of terrorism. australia is revealed to be log during the united nations for a gradual use away from fossil fuels lobbying. be log during the united nations for a gradual use away from fossil fuels the nhs is set to use a revolutionary treatment, called gene silencing, to help people with a rare genetic disease that leaves them in crippling pain. acute intermittent porphyria can lead to paralysis and is sometimes fatal. it s hoped gene silencing could also lead to therapies for a range of other untreatable diseases. ....

Bbc News , Emma Vardy , David Amess , Fossil Fuels , Gene Silencing ,

BBCNEWS BBC News October 21, 2021 16:46:00

Sir david amess. ali harbi ali, from north london, also faces charges of preparing acts of terrorism. the nhs is set to use a revolutionary treatment called gene silencing to help people with a rare genetic disease that leaves them in crippling pain. acute intermittent porphyria can lead to paralysis and is sometimes fatal. it is hoped gene silencing could also lead to therapies for a range of other untreatable diseases. here s our science correspondent, james gallagher: we remember both how traumatic it was for both me going through it and for you guys as a family watching me go through it. it was that element for me of the total pain and the sickness and eventually the paralysis and the seizures. sisters liz and sue have lived in pain that few can imagine. ....

Ali Harbi , David Amess , North London , Nhs In Wales , Gene Silencing , Science Correspondent , James Gallagher , Sisters Liz ,

BBCNEWS Breakfast October 21, 2021 05:08:00

Nearly 1,500 people have been arrested in england and wales in a week long operation against so called county lines drug networks. they involve dealers usually in big urban centres selling to customers in smaller places using dedicated phone lines. more than 130 lines were closed last week and almost £2 million of class a drugs seized. police searching for the missing fiance of a murdered american blogger have found what appear to be human remains in a park in florida. agents said items belonging to brian laundrie, who is a person of interest in gabby petito s death, were also found during the search. mr laundrie has been missing for more than a month after returning to florida from a joint trip without his partner. a new type of medicine called gene silencing is set to be used to treat a genetic disease that leaves people in crippling pain. acute intermittent porphyria can lead to paralysis ....

Phone Lines , Big Urban Centres , County Lines Drug Networks , Police Searching , Human Remains , Classa Drugs , Murdered American Blogger , 2 Million , Brian Laundrie , Person Of Interest , Gabby Petito , Gene Silencing ,

BBCNEWS BBC News at One October 21, 2021 12:25:00

With a rare genetic disease that leaves them in crippling pain. acute intermittent porphyria can lead to paralysis and is sometimes fatal. it is hoped gene silencing could also lead to therapies for a range of other untreatable diseases. here s our science correspondent james gallagher. we remember both how traumatic it was for both me going through it and for you guys as a family watching me go through it. it was that element for me of the total pain and the sickness and eventually the paralysis and the seizures. sisters liz and sue have lived in pain that few can imagine. they both have the genetic disease acute intermittent porphyria. potent opioid painkillers were a feature of their daily life, and liz was paralysed for two years. one of the times that they had to transfer me from one hospital to another because i wasn t ....

Gene Silencing , James Gallagher , Genetic Disease , Sisters Liz , Kings College Hospital , Opioid Painkillers , Wasnt Breathing ,