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New antibiotic kills pathogenic bacteria, spares healthy gut microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture. ....

United States , Paul Hergenrother , Jessica Holmes , Matt Sinclair , Rebecca Ultrich , Emad Tajkhorshid , Michelle Hassel , Chao Wen , Hyang Yeon Lee , Royj Carver Biotechnology Center , Centers For Disease , University Of Illinois Urbana Champaign , Disease Control , Antibiotic Resistance Threats , Illinois Urbana Champaign , Chris Fields , Biotechnology Center , Po Chao Wen ,

TACC Supercomputer Delves Into Protein Interactions

TACC Supercomputer Delves Into Protein Interactions
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United States , Jorge Salazar , Chao Wen , Emad Tajkhorshid , Texas Advanced Computing Center , University Of Illinois At Urbana Champaign , Po Chao Wen , ஒன்றுபட்டது மாநிலங்களில் , ஜார்ஜ் சலாசர் , குழப்பம் வென் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் இல் ஊர்பன சாம்பியன் ,