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New antibiotic kills pathogenic bacteria, spares healthy gut microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

United statesPaul hergenrotherJessica holmesMatt sinclairRebecca ultrichEmad tajkhorshidMichelle hasselChao wenHyang yeon leeRoyj carver biotechnology centerCenters for diseaseUniversity of illinois urbana champaignDisease controlAntibiotic resistance threatsIllinois urbana champaignChris fields

Guideline now recommends fecal microbiota transplant for the majority of recurrent C diff patients

Guideline now recommends fecal microbiota transplant for the majority of recurrent C diff patients
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United statesAnne peeryAmanda kabageAmerican gastroenterological associationCenters for diseaseDisease controlAntibiotic resistance threatsPractice guidelineFecal microbiota based therapiesSelect gastrointestinal diseases

AI Discovers First New Antibiotic in Over 60 Years

AI Discovers First New Antibiotic in Over 60 Years
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United statesUnited kingdomHarvard universityMassachusetts institute of technologyJames collinsInstitute for health metricsBroad instituteWorld health organizationUs centers for disease controlMassachusetts instituteAntimicrobial resistanceAntibiotic resistance threatsDisease controlAntibiotic useFood animalsUse surveillance system

Antibiotics and Antimicrobial Resistance in Swine Production

Antibiotics and Antimicrobial Resistance in Swine Production
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United statesAnne millerHeather fowlerYanhong liuCenters for diseaseUniversity of californiaDrug administrationNational pork boardStuart levyDisease controlAntibiotic resistance threatsDrug usageVeterinary feed directivesOne health approach

Experts discuss benefits and risks of different guideline-approved treatment approaches for C difficile infection

Experts discuss benefits and risks of different guideline-approved treatment approaches for C difficile infection
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United statesCarolynd alonsoJessicar allegrettiZahir kanjeeCenters for diseaseAmerican college of gastroenterologyDisease controlAntibiotic resistance threatsMedicine grand roundsBeth israel deaconess medical centerInfectious diseases societyAmerican collegeInternal medicine