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A miniature device the size and shape of an aspirin tablet could provide new options for people with cancer. Developed in the lab of Pinkas Family professor of bioengineering David Mooney, the implantable vaccine, inserted under a patient’s skin, operates like a tiny factory where immune cells of one kind are transformed to train other immune cells to eradicate tumors. The tablet-like device emits a signal that attracts dendritic cells, the messengers of the immune system, which carry information about the pathogens and toxins they encounter to other immune cells. The dendritic cells “literally crawl inside the plastic device” to be activated by freeze-dried fragments of the patient’s own tumor, Mooney explains. Once the dendritic cells have become activated, they “home to the nearest lymph node,” where they encounter T cells that they train to recognize and destroy cancer cells. The T cells then multiply and circulate through the body, dissolving the patient’s ....