A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling science.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from science.org Daily Mail and Mail on Sunday newspapers.
Neuroserpin and transthyretin are extracellular chaperones that preferentially inhibit amyloid formation science.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from science.org Daily Mail and Mail on Sunday newspapers.
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2Medical Records Management Division, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China;
3Intensive Care Unit, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China;
4Pharmacy Services, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China These authors contributed equally to this work
Correspondence: Dehong Huang
Department of Hematology and Oncology, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Chongqing, People’s Republic of China
Tel +86 23-65311341
Purpose: This study investigated the function and molecular mechanisms of miR-744-5p in multiple myeloma (MM).
Methods: miR-744-5p and SRY-related high-mobility-group box 12 (SOX12) expression in clinical tissues and MM cells was monitored by quantitative real-time polymerase chain reactions and Western blot. miR-744-5p expression in MM cells was regulated by transfection. Cell proliferation was researched by cell counting kit-8 as