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A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling

A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling
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United statesNew yorkClustal omegaHealth science research resources bankAgilent technologiesPershing square sohn cancer research allianceLaser units nikon incMos gene toolsYork communityUniversity of texas southwesternNational cancer centerGene toolsNikon incJunn terminalLife technologiesAmerican type culture

Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease

Significance Statement Mutations of PKD2 encoding polycystin-2 cause autosomal dominant polycysti

United statesAntifade mountantLos angelesViagen directGia voeltz addgeneFeng zhang addgeneEnzo biochemMetafluor imaging software molecular deviceNational institute of diabetesCare of laboratory animalsDrummond scientific coBaltimore polycystic kidney disease researchJianjie ma ohio state university medical centerScore centerJohn universityUniversity of iowa animal care

A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis

A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis
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