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Star-shaped brain cells can "turn off" neurons involved in heroin relapse

Neuroscientists from the Medical University of South Carolina report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin. ....

Peter Kalivas , Anna Kruyer , Emily Henderson , University Of South Carolina , Kalivas Lab , Kalivas Laboratory , Department Of Neuroscience , Medical University , South Carolina , Science Advances , Chemical Messenger ,

Research recognition 'nice feather in MUSC's cap'

In 2019, Stanford University began compiling a list of the most referenced – and in a way, most influential – researchers in the world. Casually known ....

Peter Kalivas , Raymond Dubois , Don Rockey , John Lemasters , Patrick Woster , Bruce Hollis , Department Of Drug Discovery , Stanford University , Biomedical Sciences , Smartstate Endowed Chair , Drug Discovery ,

Arts & Culture Newsletter: Sutton Foster shines in 'Light'


I’m
David L. Coddon,
and here’s your guide to all things essential in San Diego’s arts and culture this week.
To all those who had tickets for or planned on getting some for “An Evening With Sutton Foster,” scheduled for March 21 at Copley Symphony Hall but obviously canceled, take heart. I’ve got a consolation prize for you. For 35 bucks, you can watch
New York City Center Digital’s presentation of “Sutton Foster / Bring Me to Light.” It’s an hour’s worth of the Broadway star at her most effervescent bantering with friends and cohorts, sincerely addressing her fans and, of course, singing many beloved Broadway tunes. ....

United States , Del Norte , San Diego Museum Of Art , Copley Symphony Hall , San Diego , Long Island , Edward Elgar , Wolfgang Amadeus Mozart , Wren Rivera , Elizabeth Wistrich , Nancy Wilson , Liz Warren , Shakespeare Romeo , Rafael Payare , Michael James Rocha , George Varga , Sutton Foster , Davidl Coddon , Joaquina Kalukango , Nanceee Lewis , Ariane Mnouchkine , Steven Spielberg , Peterg Kalivas , Geoff Gonzalez , Sandy Huffaker , Anna Scipione ,

Highly specific synaptic plasticity in addiction


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Credit: Elsevier
Philadelphia, January 26, 2021 - Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or changes in the way neurons communicate with one another, drives these addictive behaviors. These lasting brain changes are at the crux of why addiction is so hard to treat.
Biological Psychiatry, published by Elsevier, now shows that players in the extracellular environment - not just at neuronal interfaces - contribute to addiction plasticity. Neurons in a brain area called the nucleus accumbens are known to undergo addiction-related plasticity. Specifically, changes at synapses of medium spiny neurons (MSN), which sense the neurotransmitter dopamine, have been associated with drug-seeking and extinction behaviors. ....

Yale New Haven Hospital , United States , Yale University , Anna Kruyer , Rhiannon Bugno , Ariana Angelis , Zachary Ellison , Peter Kalivas , Johnh Krystal , Michael Scofield , Vivian Chioma , John Krystal , Ritchy Hodebourg , Clara Bobadilla , Society Of Biological Psychiatry , Elsevier Foundation , Yale University School Of Medicine , Editorial Office , Department Of Psychiatry , Biological Psychiatry , Seeking Activate Matrix Metalloproteinases , Distinct Subpopulations , Accumbens Cells , Ana Clara Bobadilla , Yale University School , Journal Citations Reports ,