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Transforming mental health systems globally: principles and policy recommendations

Transforming mental health systems globally: principles and policy recommendations
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United States , New York , City Of , United Kingdom , Hanna Gilmore , Alikhon Aliev , Mary Butler , Zarate Jr , Lancet Psychiatry Commission , Oxford University Press , J Rural Health , Bull World Health Organ , United Nations Development Programme , World Psychiatric Association Commission , Oxford University , J Ment Health , National Academies Of Sciences , Sustainable Development Goals , World Health Forum , Community Ment Health , Health Serv Res , International Patient Decision Aid Standards Collaboration , Un Development Programme , National Academies , Healthy Programme , World Health Organization ,

Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial

Targeting CLDN18.2 with zolbetuximab significantly prolonged progression-free survival
and overall survival when combined with mFOLFOX6 versus placebo plus mFOLFOX6 in patients
with CLDN18.2-positive, HER2-negative, locally advanced unresectable or metastatic
gastric or gastro-oesophageal junction adenocarcinoma. Zolbetuximab plus mFOLFOX6
might represent a new first-line treatment in these patients. ....

Van Cutsem , Japanese Gastric Cancer Association , Chinese Society Of Clinical Oncology , Global Burden , Disease Study , Chinese Society , Clinical Oncology , Gastric Cancer Treatment Guidelines , Clin Med , Clin Oncol , Practice Guideline , Pers Med , Cell Biol , Cancer Res ,

A New Paradigm for Testing Psychiatric Drugs Is Needed

We need a stricter test of psychiatric drugs with patient-relevant outcomes, real comparators, long-term outcomes, and assessment of harms. ....

New York , United States , United Kingdom , New Zealand , City Of , New Zealanders , Marie Jensen , Adolesc Psychopharmacol , Le Noury , American Psychiatric Association , Institute For Scientific Freedom , Spanish Working Group , Psychiatr Ment Health Nurs , J Mens Health , Palgrave Macmillan , Drug Administration , Perseus Books Group , Qual Health Res , National Institute For Health , American Psychiatric Publishing Group , Thomas Jobe Fund , British Psychiatric Morbidity , York University , Scientific Freedom , Hamilton Depression Rating Scale , Negative Syndrome Scale ,