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Metastatic HER2+ Breast Cancer: Current Strategies and Ongoing Trials

Experts discuss the CLEOPATRA trial outcomes, taxane nuances, and evolving strategies in first-line treatment. They review practical considerations and ongoing trials and dive into the dynamic landscape of managing metastatic HER2+ breast cancer, anticipating transformative developments. ....

Claudine Isaacs , Priyanka Sharma , Heather Mcarthur , Joyce Oshaughnessy , Translational Breast Cancer Research Consortium , Peer Exchange , Joyceo Shaughnessy , Adjuvant Setting , Nccn Guidelines , Neoadjuvant Therapy , Adjuvant Therapy ,

Exploring Therapeutic Avenues in HER2+ Breast Cancer

Experts delve into post–KATHERINE trial discussions, examining data and its impact on residual disease. They highlight unmet needs, emphasizing the ongoing CompassHER2 RD trial’s potential to address challenges, especially regarding brain metastases. ....

Heather Mcarthur , Joyce Oshaughnessy , Priyanka Sharma , Claudine Isaacs , Peer Exchange , Joyceo Shaughnessy , Adjuvant Setting , Nccn Guidelines , Neoadjuvant Therapy , Adjuvant Therapy ,

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria the energy-generating cell organelles in each neuron. ....

Comunidad Autonoma De Cataluna , Pais Vasco , Ismael Izquierdo Villalba , Gemma Marfany , Eduardo Soriano , Sanna Mar , Serena Mirra , Xavier Navarro , Ub Department Of Genetics , University Hospital Of Donostia , Department Of Cell Biology , Institute Of Biomedicine , Institute Of Molecular Biology Barcelona , National Centre Of Cardiovascular Research Carlos , Institute Of Neurosciences , University Of Barcelona , Autonomous University Of Barcelona , Biomedical Networking Research On Fragility , Spanish National Research Council , Biomedical Research Networking Centre On Neurodegenerative Diseases , Rare Diseases Networking Biomedical Research Centre , Science Signaling , Professor Eduardo Soriano , Biomedical Research Networking Centre , Neurodegenerative Diseases , Molecular Biology ,

Evolving Strategies in Adjuvant HER2+ Breast Cancer

Experts analyze adjuvant therapy based on preoperative responses. The discussion unveils standard practices, recent KATHERINE trial data, and considerations for residual disease, offering profound insights into tailoring treatment for improved outcomes. ....

Priyanka Sharma , Joyce Oshaughnessy , Heather Mcarthur , Claudine Isaacs , Peer Exchange , Joyceo Shaughnessy , Adjuvant Setting , Nccn Guidelines , Neoadjuvant Therapy , Adjuvant Therapy ,