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Late-toxicity burden high among survivors of high-risk neuroblastoma

CHICAGO — Survivors of high-risk neuroblastoma face a substantial burden of late toxicity, according to study results presented at ASCO Annual Meeting.Prevalence of some late effects vary by treatment received, findings showed. ....

University Of Chicago , United States , Tarao Henderson , Bymark Leiser , Oren Becher , Mindy Valcarcel , Chidlren Oncology Group , National Academies Of Medicine , Sciences Committee On Disability , National Academies , Sciences Committee , Young Adult Survivorship Center , Oncology Group , Oncology Group Based ,

Combination therapy shows preliminary antitumor activity in pediatric neuroblastoma

The combination of olaparib and the investigational ATR inhibitor ceralasertib induced antitumor responses in children and adolescents with DNA repair-deficient tumors, according to phase 1 results of the AcSé-ESMART trial.The data, presented at American Association for Cancer Research Annual Meeting, also showed ceralasertib (AZD6738, AstraZeneca) plus olaparib (Lynparza, AstraZeneca) — a ....

United States , United Kingdom , Susanne Gatz , Oren Becher , Mindy Valcarcel , Timothy Yap , Fondation Gustave Roussy , Bydrew Amorosi , Cancer Research United Kingdom , Leukaemia Group , Genomic Sciences , French Institut National De Cancer , University Of Birmingham Institute Cancer , American Association For Cancer Research Annual Meeting , Little Princess Trust Children Cancer , American Association , Cancer Research Annual Meeting , Astrazeneca France , Little Princess , Adobe Stock , Europe Based Acs ,

Nanoparticles Target Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity

Nanoparticles Target Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity
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Praveen Raju , Oren Becher , Steven Ravitch , Daniel Heller , Icahn School Of Medicine At Mount Sinai , National Institutes Of Health , Jack Martin Fund Division Of Pediatric Hematology , Researchers At Mount Sinai Health System , Head Of The Cancer Nanomedicine Laboratory , Foundation Game Changer Grant , Memorial Sloan Kettering Cancer Center , Mount Sinai Health System , Spinal Tumor Center , Mount Sinai Kravis Children , Nature Materials , Icahn School , Cancer Nanomedicine Laboratory , Molecular Pharmacology Program , National Institutes , Chadtough Defeat , Game Changer Grant , Jack Martin Fund Division , Pediatric Hematology Oncology , Steven Ravitch Chair , Icahn Mount Sinai ,

Improved Anti-Tumor Drug Delivery Across Blood–Brain Barrier

Researchers have developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anti-cancer drugs to treat brain tumors in children. ....

Praveen Raju , Oren Becher , Steven Ravitch , Daniel Heller , National Institutes Of Health , Technology Network , Jack Martin Fund Division Of Pediatric Hematology , Mount Sinai Health System , Head Of The Cancer Nanomedicine Laboratory , Foundation Game Changer Grant , Memorial Sloan Kettering Cancer Center , Spinal Tumor Center , Mount Sinai Kravis Children , Associate Professor , Icahn School , Cancer Nanomedicine Laboratory , Molecular Pharmacology Program , National Institutes , Chadtough Defeat , Game Changer Grant , Jack Martin Fund Division , Pediatric Hematology Oncology , Steven Ravitch Chair , Icahn Mount Sinai ,

Jack Martin Fund Gives $3.5 Million to Mount Sinai Kravis Children's Hospital to Establish State-of-the-Art Child and Adolescent Imaging Center

Jack Martin Fund Gives $3.5 Million to Mount Sinai Kravis Children's Hospital to Establish State-of-the-Art Child and Adolescent Imaging Center
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New York , United States , Mark Zeller , Alan Feldman , Lisam Satlin , Oren Becher , Herberth Lehman , Margaret Pastuszko , Chris Mongeluzo , Fernando Ferrer , Blau Center , Lucy Clark Department Of Pediatrics , Jack Martin Fund , Division Of Pediatric Hematology , Tumor Center , Imaging Center , Icahn School Of Medicine At Mount Sinai , Creative Arts Therapy Program , Jack Martin Fund Division Of Pediatric Hematology , Jack Martin Fund Child , Mount Sinai Health System , Mount Sinai Hospital , Adolescent Imaging Center , Mount Sinai Kravis Children , Mount Sinai Children , Spinal Tumor Center ,