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Merck (MRK) and Eisai Provide Update on Two Phase 3 Trials Evaluating KEYTRUDA Plus LENVIMA in Patients With Certain Types of Metastatic Non-Small Cell Lung Cancer

Merck (MRK) and Eisai Provide Update on Two Phase 3 Trials Evaluating KEYTRUDA Plus LENVIMA in Patients With Certain Types of Metastatic Non-Small Cell Lung Cancer
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United States , Corina Dutcus , Gregory Lubiniecki , Oncology At Eisai Inc , Global Clinical Development , Merck Research Laboratories , Vice President , Merck Research , Senior Vice President ,

LEAP-010 Trial Discontinued After OS Projection With Pembrolizumab/Lenvatinib in Metastatic HNSCC

The combination of pembrolizumab and lenvatinib demonstrated a statistically significant improvement in progression-free survival and objective response rate but failed to improve overall survival compared with pembrolizumab plus placebo as frontline therapy for patients with recurrent or metastatic head and neck squamous cell carcinoma. ....

United States , Corina Dutcus , Gregory Lubiniecki , Oncology At Eisai Inc , Global Clinical Development At Merck Research Laboratories , Global Clinical Development , Data Monitoring Committee , European Union , Merck Research Laboratories , Eisai Inc , Pembrolizumab And Lenvatinib , Pembrolizumab Plus Placebo , Patients With Recurrent Or Metastatic Head And Neck Squamous Cell Carcinoma , Leap 010 Trial , Eisai Inc ,