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Closer Look at Cartilage Regeneration: Micromechanical Mismatches Impact Transplants miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Researchers bioprint tissue-like constructs capable of controlled, complex shape change miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
New 4D Hydrogels can Change Shape in Response to Stimuli Written by AZoMMar 2 2021 For a long time, tissue engineering has relied on geometrically static scaffolds that are seeded with cells in the laboratory to make new tissues and even organs. 4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues. Image Credit: Aixiang Ding. Generally, the scaffolding material is a biodegradable polymer structure that is provided with cells, and if the cells are supplied with proper nutrients, then they develop into a tissue as the basic scaffold biodegrades. However, this model disregards the exceptionally dynamic morphological processes that form the basis of the natural growth of tissues. ....
E-Mail IMAGE: 4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues view more Credit: Aixiang Ding Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs. The scaffolding material usually a biodegradable polymer structure is supplied with cells and the cells, if supplied with the right nutrients, then develop into tissue as the underlying scaffold biodegrades. But this model ignores the extraordinarily dynamic morphological processes that underlie the natural development of tissues. Now, researchers at the University of Illinois Chicago have developed new 4D hydrogels 3D materials that have the ability to change shape over time in response to stimuli that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals. ....
E-Mail IMAGE: The 4D material changes shape in response to water. The grey side of the material in the image absorbs water faster than the blue side, causing it to bend into. view more Credit: Yu Bin Lee New hydrogel-based materials that can change shape in response to physiological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago. In a new paper published in the journal Advanced Functional Materials, the research team led by Eben Alsberg, the Richard and Loan Hill Professor of Biomedical Engineering that developed the substances show that the unique materials can curl into tubes in response to water, making the materials good candidates for bioengineering blood vessels or other tubular structures. ....