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4D Hydrogels the Shape of Things to Come in Tissue Engineering

4D Hydrogels the Shape of Things to Come in Tissue Engineering
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United States , Sharon Parmet , Eben Alsberg , University Of Illinois Chicago , National Heart , Blood Institute , National Institute Of Biomedical Imaging , Illinois Chicago , Advanced Sciencestudy , Loan Hill Professor , Biomedical Engineering , National Institutes , National Institute , Skin Diseases , Biomedical Imaging , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் சிகாகோ , தேசிய இதயம் , இரத்தம் நிறுவனம் , தேசிய நிறுவனம் ஆஃப் உயிர் மருத்துவ இமேஜிங் , இல்லினாய்ஸ் சிகாகோ , கடன் மலை ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , தேசிய நிறுவனங்கள் , தேசிய நிறுவனம் , தோல் நோய்கள் ,

New 4D Hydrogels can Change Shape in Response to Stimuli

New 4D Hydrogels can Change Shape in Response to Stimuli
Written by AZoMMar 2 2021
For a long time, tissue engineering has relied on geometrically static scaffolds that are seeded with cells in the laboratory to make new tissues and even organs.
4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues. Image Credit: Aixiang Ding.
Generally, the scaffolding material is a biodegradable polymer structure that is provided with cells, and if the cells are supplied with proper nutrients, then they develop into a tissue as the basic scaffold biodegrades. However, this model disregards the exceptionally dynamic morphological processes that form the basis of the natural growth of tissues. ....

United States , Rui Tang , Oju Jeon , Eben Alsberg , Jin Lee , University Of Illinois Chicago , Study Co , National Heart , Blood Institute , National Institute Of Biomedical Imaging , Postdoctoral Research , Illinois Chicago , Advanced Science , Study Corresponding Author , Loan Hill Professor , Biomedical Engineering , Study Co First Author , Postdoctoral Research Associate , Sang Jin Lee , National Institutes , National Institute , Skin Diseases , Biomedical Imaging , ஒன்றுபட்டது மாநிலங்களில் , ரயீ டாங் , ஓஜூ ஜீன் ,

4D bioengineering materials bend, curve like natural tissue

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IMAGE: 4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues
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Credit: Aixiang Ding
Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs. The scaffolding material usually a biodegradable polymer structure is supplied with cells and the cells, if supplied with the right nutrients, then develop into tissue as the underlying scaffold biodegrades. But this model ignores the extraordinarily dynamic morphological processes that underlie the natural development of tissues.
Now, researchers at the University of Illinois Chicago have developed new 4D hydrogels 3D materials that have the ability to change shape over time in response to stimuli that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals. ....

United States , Rui Tang , Oju Jeon , Eben Alsberg , Jin Lee , University Of Illinois Chicago , National Heart , Blood Institute , National Institute Of Biomedical Imaging , Illinois Chicago , Advanced Science , Loan Hill Professor , Biomedical Engineering , Aixiang Ding , Sang Jin Lee , National Institutes , National Institute , Skin Diseases , Biomedical Imaging , Chemistry Physics Materials Sciences , ஒன்றுபட்டது மாநிலங்களில் , ரயீ டாங் , ஓஜூ ஜீன் , ஜின் லீ , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் சிகாகோ , தேசிய இதயம் ,

New hydrogel-based materials show promise for tissue engineering

New hydrogel-based materials that can change shape in response to psychological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago. ....

United States , Eben Alsberg , Emily Henderson , University Of Illinois Chicago , Advanced Functional Materials , Loan Hill Professor , Biomedical Engineering , Industrial Engineering , Tissue Engineering , Blood Vessels , Embryonic Development , Next Generation , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் சிகாகோ , கடன் மலை ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , தொழில்துறை பொறியியல் , திசு பொறியியல் , இரத்தம் நாளங்கள் , அடுத்தது ஜெநரேஶந் ,

New shape-changing 4D materials hold promise for morphodynamic tissue engineering

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IMAGE: The 4D material changes shape in response to water. The grey side of the material in the image absorbs water faster than the blue side, causing it to bend into.
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Credit: Yu Bin Lee
New hydrogel-based materials that can change shape in response to physiological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago.
In a new paper published in the journal
Advanced Functional Materials, the research team led by Eben Alsberg, the Richard and Loan Hill Professor of Biomedical Engineering that developed the substances show that the unique materials can curl into tubes in response to water, making the materials good candidates for bioengineering blood vessels or other tubular structures. ....

United States , Oju Jeon , Eben Alsberg , Jin Lee , University Of Illinois Chicago , National Institute Of Biomedical Imaging , Advanced Functional Materials , Loan Hill Professor , Sang Jin Lee , Aixiang Ding , Derrick Wells , National Institutes , National Institute , Arthritis And Musculoskeletal , Skin Diseases , Biomedical Imaging , Chemistry Physics Materials Sciences , ஒன்றுபட்டது மாநிலங்களில் , ஓஜூ ஜீன் , ஜின் லீ , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் சிகாகோ , தேசிய நிறுவனம் ஆஃப் உயிர் மருத்துவ இமேஜிங் , கடன் மலை ப்ரொஃபெஸர் , பாடினார் ஜின் லீ , டெரிக் கிணறுகள் , தேசிய நிறுவனங்கள் ,