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Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered. ....

Kazuhiro Fukumura , Michael Sattler , Akila Mayeda , Fujita Health University , Fujita Health , Cell Reports , N Vitro , N Vivo ,

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections. ....

United States , Dalef Kreitler , Olga Rechkoblit , Angeliki Buku , Aneel Aggarwal , Jithesh Kottur , Daniela Sciaky , National Institutes Of Health , Centers For Disease , Beamline Scientist At Brookhaven National Laboratory , Mount Sinai Health System , Icahn School Of Medicine At Mount Sinai , Simons Foundation , Sinai Health , Icahn School , Mount Sinai , Nature Structural , Molecular Biology , Co Senior Author , Pharmacological Sciences , Icahn Mount , Disease Control , Assistant Professor , Icahn Mount Sinai , Brookhaven National , National Institutes ,

When mass spectrometry redefines the pharma industry

In this new episode of omg OMx, Kate Stumpo speaks to Bruker's Mike Greig about the incredible
potential of mass spectrometry in pharma. ....

United States , Buffalo Grove High School , Bruker Mike Greig , Louis Castel , Mike Greigexecutive Directorbruker , Mike Greig , Chris Hendrickson , Fox Shutterstock , Kate Stumpo , Jared Rader , Bruker Life Sciences Mass Spectrometryjan , Time Magazine , Global Pharma Biopharma Market At Bruker Scientific , While At Isis Pharmaceuticals , Bruker Life Sciences Mass Spectrometry , Isis Pharmaceuticals , Sponsored Content , Analytical Chemistry , Executive Director , Biopharma Market , Bruker Scientific , Senior Market Manager , Trapped Ion Mobility , Extreme Resolution , Isotopic Fine Structure , Mass Spectrometry ,

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. For the first time, UC Riverside scientists have shown they can slow its progression in flies and worms, opening the door to human treatments. ....

Danielle Ellis , Nancym Bonini , Weifeng Gu , X William Yang , Yinsheng Wang , University Of Pennsylvania , Genetic Information , Huntington 39s Disease ,

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects. ....

University Of California Santa Cruz , Genomic Pre Trained Network , Uniform Manifold Approximation , California Santa Cruz , Genome Browser ,