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Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population. ....

United Kingdom , United States , Joanne Ngeow , Singapore Lee Kong Chian School Of Medicine , National Comprehensive Cancer Network , Lancet Regional Health , University Of Malaya , University Of Cambridge , National Cancer Centre Singapore , Singapore National Precision Medicine Programme , Genome Institute Of Singapore , Cancer Research Malaysia , University Of Nottingham Malaysia , Head Of The Cancer Genetics Service , Nanyang Technological University , National Precision Medicine Programme , Malaysian Chinese , Singaporean Chinese , Malaysian Indians , Singaporean Indians , East Asians , South Asians , North America , Co Senior Author , Associate Professor , Genomic Medicine ,

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections. ....

United States , Dalef Kreitler , Olga Rechkoblit , Angeliki Buku , Aneel Aggarwal , Jithesh Kottur , Daniela Sciaky , National Institutes Of Health , Centers For Disease , Beamline Scientist At Brookhaven National Laboratory , Mount Sinai Health System , Icahn School Of Medicine At Mount Sinai , Simons Foundation , Sinai Health , Icahn School , Mount Sinai , Nature Structural , Molecular Biology , Co Senior Author , Pharmacological Sciences , Icahn Mount , Disease Control , Assistant Professor , Icahn Mount Sinai , Brookhaven National , National Institutes ,

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups. ....

New South Wales , Lily Ramsey , Fabio Luciani , Peter Doherty Institute For Infection , Doherty Institute , Immunity Doherty Institute , Senior Research , University Of Melbourne Professor Katherine Kedzierska , Nature Immunology , Peter Doherty Institute , Senior Research Fellow , Professor Katherine Kedzierska , Associate Professor Fabio Luciani , Associate Professor Luciani , Associate Professor , Co Senior Author , Immune System ,

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning. ....

Van Allen , Danielle Ellis , Toni Choueiri , Jackson Nyman , Sabina Signoretti , Eliezer Van Allen , Lank Center , Division Of Population Sciences At Dana Farber , Cell Reports Medicine , Co Senior Author , Population Sciences , Genitourinary Oncology , Deep Learning , Kidney Cancer , Clinical Trial , Renal Cell Carcinoma ,

Breast milk proteins linked to abundance of beneficial bacteria in infants

More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors. ....

Yau Szeto , Lily Ramsey , Nutrition Institute , Tsinghua University , Image Credit , Yili Maternal , Infant Nutrition Institute , Co Senior Author , Breast Milk , Immune System , Inflammatory Bowel Disease ,