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Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

Singapore
Malaysia
Cambridge
Cambridgeshire
United-kingdom
Nanyang
Henan
China
United-states
Nottingham
Chinese
Malaysian

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

Sydney
New-south-wales
Australia
Lily-ramsey
Fabio-luciani
Peter-doherty-institute-for-infection
Doherty-institute
Immunity-doherty-institute
Senior-research
University-of-melbourne-professor-katherine-kedzierska
Nature-immunology
Peter-doherty-institute

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

Van-allen
Danielle-ellis
Toni-choueiri
Jackson-nyman
Sabina-signoretti
Eliezer-van-allen
Lank-center
Division-of-population-sciences-at-dana-farber
Cell-reports-medicine
Co-senior-author
Population-sciences
Genitourinary-oncology

Breast milk proteins linked to abundance of beneficial bacteria in infants

More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors.

Beijing
China
Yili
Sichuan
Chinese
Yau-szeto
Lily-ramsey
Nutrition-institute
Tsinghua-university
Image-credit
Yili-maternal
Infant-nutrition-institute

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