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Novartis atrasentan Phase III data show clinically meaningful proteinuria reduction further advancing company's IgA nephropathy (IgAN) portfolio

In the ALIGN study, atrasentan, in addition to supportive care with a renin-angiotensin system (RAS) inhibitor, demonstrated a statistically significant 36.1%. ....

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Novartis atrasentan Phase III data show clinically

Novartis atrasentan Phase III data show clinically
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United States , Lambers Heerspink , Sloan Simpson , Michael Meo , Satoshi Sugimoto , Jonathan Graham , Imke Kappes , Marlena Abdinoor , Loreto Mda , Bartonm Endothelin , Nicole Zinsli Somm , Parag Mahanti , Isabella Zinck , Novartis Fabhalta , European Renal Association , Exchange Commission , Fibrotic Transcriptional Networks , Endpoint Analysis , Atrasentan Shows Significant Reduction , Iga Nephropathy , Endothelin Receptor Typeb Expression , Glomerular Diseases , Receptor Immunoreactivity , Endothelin Antagonists , Chronic Kidney , Improving Global Outcomes ,

Novartis Pharma AG: Novartis atrasentan Phase III data show clinically meaningful proteinuria reduction further advancing company's IgA nephropathy (IgAN) portfolio

In the ALIGN study, atrasentan, in addition to supportive care with a renin-angiotensin system (RAS) inhibitor, demonstrated a statistically significant 36.1% proteinuria (protein in urine) reduction vs. ....

United States , Sloan Simpson , Nicole Zinsli Somm , Lambers Heerspink , Jonathan Graham , Satoshi Sugimoto , Parag Mahanti , Marlena Abdinoor , Imke Kappes , Isabella Zinck , Novartis Fabhalta , Michael Meo , Loreto Mda , Bartonm Endothelin , Exchange Commission , European Renal Association , Fibrotic Transcriptional Networks , Endpoint Analysis , Atrasentan Shows Significant Reduction , Iga Nephropathy , Endothelin Receptor Typeb Expression , Glomerular Diseases , Receptor Immunoreactivity , Endothelin Antagonists , Chronic Kidney , Improving Global Outcomes ,

Novartis Nabs FDA Nod for Rare Disease Drug Rival to AstraZeneca Meds

FDA approval of Novartis’s Fabhalta makes the drug the first approved oral therapy for rare blood disorder paroxysmal nocturnal hemoglobinuria. With clinical data showing superiority versus two infused AstraZeneca drugs, Novartis’s pill is well-positioned to take market share from those blockbuster products. ....

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