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Novartis atrasentan Phase III data show clinically meaningful proteinuria reduction further advancing company s IgA nephropathy (IgAN) portfolio

In the ALIGN study, atrasentan, in addition to supportive care with a renin-angiotensin system (RAS) inhibitor, demonstrated a statistically significant 36.1%.

United statesJonathan grahamMarlena abdinoorSloan simpsonLoreto mdaParag mahantiLambers heerspinkBartonm endothelinMichael meoNovartis fabhaltaPrnewswire novartisEuropean renal associationFibrotic transcriptional networksNovartis pharmaceuticals corporationExchange commissionEndpoint analysis

Novartis atrasentan Phase III data show clinically

Novartis atrasentan Phase III data show clinically
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United statesLambers heerspinkSloan simpsonMichael meoSatoshi sugimotoJonathan grahamImke kappesMarlena abdinoorLoreto mdaBartonm endothelinNicole zinsli sommParag mahantiIsabella zinckNovartis fabhaltaEuropean renal associationExchange commission

Novartis Pharma AG: Novartis atrasentan Phase III data show clinically meaningful proteinuria reduction further advancing company s IgA nephropathy (IgAN) portfolio

In the ALIGN study, atrasentan, in addition to supportive care with a renin-angiotensin system (RAS) inhibitor, demonstrated a statistically significant 36.1% proteinuria (protein in urine) reduction vs.

United statesSloan simpsonNicole zinsli sommLambers heerspinkJonathan grahamSatoshi sugimotoParag mahantiMarlena abdinoorImke kappesIsabella zinckNovartis fabhaltaMichael meoLoreto mdaBartonm endothelinExchange commissionEuropean renal association

Novartis iptacopan meets primary endpoint in new rare kidney disease trial

Novartis investigational iptacopan Phase III study demonstrates clinically meaningful and highly statistically significant proteinuria reduction in patients with IgA nephropathy (IgAN)Ad hoc announcement pursuant to Art. 53 LRPhase III APPLAUSE-IgAN study met its pre-specified interim analysis primary endpoint, demo.

United statesShreeram aradhyeNovartis pharmaceuticalsEuropean medicines agencyExchange commissionNovartis biomedical researchChief medical officerChinook therapeuticsAbout igaTherapy designationNatl acadAlternative complement pathway with iptacopanTreat iga nephropathyKidney intEmerging roleComplement proteins

Novartis Pharma AG: Novartis investigational atrasentan Phase III study demonstrates clinically meaningful and highly statistically significant proteinuria reduction in patients with IgA nephropathy (IgAN)

Novartis Pharma AG: Novartis investigational atrasentan Phase III study demonstrates clinically meaningful and highly statistically significant proteinuria reduction in patients with IgA nephropathy (IgAN)
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United statesMichael meoNicole zinsli sommIhre chancenMarlena abdinoorIndiens wirtschaftRichard jarvisJonathan grahamLambers heerspinkSatoshi sugimotoSamir shahParag mahantiSloan simpsonZain iqbalShreeram aradhyeImke kappes