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According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes. ....
Engineered protein inspired by nature may help plastic plague eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Researchers solve a puzzle to design larger proteins eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Read Time: Efforts to enhance the ability of proteins to resist breaking down, or âdenaturingâ, at high temperatures is one of the hottest topics in biotech. Researchers have now identified some of the principles behind how this works, potentially opening up a raft of industrial applications for designer proteins. Bioengineers have found why proteins that are designed from scratch tend to be more tolerant to high temperatures than proteins found in nature. Natural proteins with high âthermostabilityâ are prized for their wide range of applications, from baking and paper-making to chemical production. Efforts to enhance protein thermostabilityâand to discover the principles behind thisâis one of the hottest topics in biotech. ....
de novo protein with most of the core filled with valine residues (green). Ten hydrophobic residues were mutated to smaller valine residues. This de Credit: NINS/IMS Bioengineers have found why proteins that are designed from scratch tend to be more tolerant to high temperatures than proteins found in nature. Natural proteins with high thermostability are prized for their wide range of applications, from baking and paper-making to chemical production. Efforts to enhance protein thermostability and to discover the principles behind this is one of the hottest topics in biotech. The latest discoveries, described in the Proceedings of the National Academy of Sciences on November 23, 2020, open up the possibility of lab-made proteins with even better industrial applicability. ....