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Breakthrough in designing complicated all-α protein structures

Breakthrough in designing complicated all-α protein structures
asiaresearchnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaresearchnews.com Daily Mail and Mail on Sunday newspapers.

Japan General , Naohiro Kobayashi , Toshio Nagashima , Toshihiko Sugiki , Takahiro Kosugi , Toshimichi Fujiwara , Koya Sakuma , Naoya Kobayashi , Takeshi Murata , Nobuyasu Koga , Institute For Molecular Science , Exploratory Research Center On Life , Nagoya University , Protein Data Bank , National Institutes Of Natural Sciences , Institute For Protein Research , Osaka University , Kitasato University , Chiba University , University For Advanced , Nara Institute Of Science , Exploratory Research Center , Living Systems , National Institutes , Natural Sciences , Graduate University ,

First observation of structures resulting fro

<p style="text-align:justify">Antibodies hold promise as therapeutic agents. However, their tendency to aggregate poses significant challenges to drug development. In a groundbreaking study, researchers from Japan now provide novel insights into the structure formed due to 3D domain swapping of the antibody light chain, the part of the antibody contributing to antigen binding. Their findings are expected to lead to improvements in antibody quality and the development of novel drugs.</p>
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Japan General , Kowit Hengphasatporn , Yasuteru Shigeta , Takahiro Sakai , Emi Hifumi , Hideaki Ogata , Ryo Fujiki , Tsuyoshi Mashima , Naoya Kobayashi , Taizo Uda , Supramolecular Chemistry Lab , Nara Institute Of Science , Nature Communications , Shun Hirota , Nara Institute , Thermodynamic Insights , Antibody Light Chain Tetramer Formation , Lian Duan , Functional Supramolecular Chemistry Lab , Kansai Science City ,

Engineered protein inspired by nature may help plastic plague

Engineered protein inspired by nature may help plastic plague
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Ryota Iino , Naoya Kobayashi , Akihiko Nakamura , Nobuyasu Koga , Technology Of Japan , Exploratory Research Center On Life , Excells Special Collaboration Program , Initiative For Excellent Young Researchers , Sumitomo Foundation , American Chemical Society , Institute For Molecular Science , Department Of Applied Life Sciences , National Institutes Of Natural Sciences , Shizuoka University , School Of Physical Sciences , University For Advanced Studies , Ministry Of Education , American Chemical , Molecular Science , National Institutes , Natural Sciences , Physical Sciences , Graduate University , Advanced Studies , Applied Life Sciences ,