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Octopuses Do Something Really Strange to Their Genes

Octopuses Do Something Really Strange to Their Genes
theatlantic.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from theatlantic.com Daily Mail and Mail on Sunday newspapers.

United States , Tel Aviv , Sy Montgomery , Joshua Rosenthal , Carrie Albertin , Jianzhi Zhang , Noa Liscovitch Brauer , Kazuko Nishikura , Michael Bentley Flickr , Daniel Rokhsar , Eli Eisenberg At Tel Aviv University , University Of Michigan , Marine Biological Laboratory , Wistar Institute , University Of California , University Of Chicago , Eli Eisenberg , Tel Aviv University , Michael Bentley ,

When octopuses get cold, they rewire their brains and hijack their RNA

This is a seriously impressive biological ability. ....

United States , Saint Francis , Marine Biological Laboratory , Matthew Birk , Matthewj Dominguez , Joshua Rosenthal , Noa Liscovitch Brauer , J Damon Hoff , Joshua Jc Rosenthal , Itamar Twersky , Matthewa Birk , Kristenj Verhey , Yang Yue , Eli Eisenberg , Rogert Hanlon , R Bryan Sutton , Sean Mcneme , Saint Francis University , Aviv University , Marine Biological Laboratory Of Woods Hole , Woods Hole , Marine Biological , Tel Aviv University ,

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer
In a new resource for the scientific community, published today in
Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.
With this technology, they profile changes in genome organization and create a large-scale atlas of how loss of individual chromatin-altering enzymes impacts the human genome. The new method harnesses the programmability of the gene editing system CRISPR to knock-out nearly all chromatin-related genes in parallel, offering researchers deeper insights into the role of DNA accessibility in cancer and in rare diseases involving chromatin. ....

New York , United States , New York University , Neville Sanjana , Noa Liscovitch Brauer , Jay Shendure , Emily Henderson , Sanjana Lab , Innovation Technology Lab , York Genome Center , University Of Washington , Grossman School Of Medicine , Study Co , York University , Nature Biotechnology , New York Genome Center , Study Co Author , Postdoctoral Fellow , Antonino Montalbano , Core Faculty Member , Assistant Professor , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , புதியது யார்க் பல்கலைக்கழகம் , நெவில் சஞ்சனா , ஜெய் ஷெண்டுரே ,

Single-cell CRISPR technology deciphers role of chromatin accessibility in cancer

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IMAGE: CRISPR-sciATAC is a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene editing system.
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Credit: Sanjana Lab of New York Genome Center and NYU
NEW YORK, NY (April 29, 2021) - In a new resource for the scientific community, published today in
Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. With this technology, they profile changes in genome organization and create a large-scale atlas of how loss of individual chromatin-altering enzymes impacts the human genome. The new method harnesses the programmability of the gene ed ....

New York , United States , Memorial Sloan Kettering Cancer Center , Rockefeller University , New York University , Cold Spring Harbor Laboratory , Hospital For Special Surgery , American Museum Of Natural History , Columbia University , Neville Sanjana , Noa Liscovitch Brauer , Karen Zipern , Jay Shendure , Sanjana Lab , York Genome Center , Rutgers Cancer Institute Of New Jersey , University Of Washington , Grossman School Of Medicine , Roswell Park Cancer Institute , York University , Hackensack Meridian Health , York Stem Cell Foundation , Northwell Health , Albert Einstein College Of Medicine , Princeton University , Stony Brook University ,