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Liso-Cel Demonstrates Durable Efficacy in Relapsed/Refractory CLL/SLL

Lisocabtagene maraleucel elicited durable responses in patients with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. ....

Niravn Shah , College Of Wisconsin , Cellular Therapy Meetings , Medical College , Liso Cel , Isocabtagene Maraleucel Liso Cel Breyanzi , Phase 1 2 Transcend Cll 004 Trial Nct03331198 ,

Bispecific Antibodies and Noncovalent BTK Inhibitors Expand Horizons in DLBCL and MCL

Catherine C. Coombs, MD, spotlights the use of bispecific antibodies in diffuse large B-cell lymphoma and pirtobrutinib in mantle cell lymphoma. ....

United States , University Of California Irvine , Catherinec Coombs , Niravn Shah , Swetha Kambhampati , Department Of Medicine , College Of Wisconsin , Division Of Hematology , School Of Medicine , California Irvine , Onclive Institutional Perspectives , Medical College , Mantle Cell Lymphoma , Largeb Cell Lymphoma , Bispecific Antibodies ,

Pirtobrutinib Monotherapy Demonstrates Early Activity in R/R Follicular Lymphoma

Treatment with single-agent pirtobrutinib showed encouraging efficacy with a tolerable safety profile in a cohort of heavily pretreated patients with relapsed/refractory follicular lymphoma. ....

Niravn Shah , College Of Wisconsin , Medical College , Ann Arbor , Nash Meeting , Follicular Lymphoma , Phase 1 2 Bruin Trial Nct03740529 ,

Standards of Care and Novel Therapies Converge to Propel Advances in Follicular Lymphoma

Christopher R. Flowers, MD, MS, and colleagues shed light on recent updates in the treatment armamentarium for follicular lymphoma and highlight ongoing investigations of novel agents and combinations. ....

United States , Sameh Gaballa , Vickia Morrison , Dai Chihara , Nathan Fowler , Matthew Lunning , Niravn Shah , Lymphomes Folliculaires , Hun Ju Lee , University Of Nebraska Medical Center , University Of Minnesota , Moffitt Cancer Center , Division Of Cancer Medicine , College Of Wisconsin , University Of Texas Md Anderson Cancer Center , Department Of Lymphoma , Scientific Interchange , Cancer Medicine , Cancer Center , Treatment Arena , Frontline Approaches , Etude Des Lymphomes Folliculaires , Medical College , Second Line Treatments , Nebraska Medical Center , Current And Emerging Therapeutic Advances In Follicular Lymphoma ,

Lilly Announces Details of Pirtobrutinib Presentations in B-Cell Malignancies at 2023 ASH Annual Meeting

/PRNewswire/ Eli Lilly and Company (NYSE: LLY) today announced that data from studies of pirtobrutinib, a non-covalent (reversible) Bruton s tyrosine kinase. ....

San Diego Convention Center , United States , San Diego , Jun Zhu , Kyle Owens , Williamg Wierda , Krish Patel , Nitin Jain , Joe Fletcher , Eli Lilly , Hyattsan Diego , Jonathonb Cohen , Jenniferr Brown , Lindseye Roeker , Niravn Shah , Jennifera Woyach , Prnewswire Eli Lilly , Laboratory Abnormalities , Lilly United States , American Society Of Hematology , Outcomes Research , Exchange Commission , American Society , Annual Meeting , Mantle Cell Lymphoma , Efficacy Including High Risk Subgroup Analyses ,