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Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

Researchers evaluated the efficacy, immunogenicity, and safety of a novel SARS-CoV-2 linear deoxyribonucleic acid vaccine in ferret models delivered using intramuscular injection and electroporation. ....

World Health Organization , Animal Model , Coronavirus Disease Covid 19 , Ars Cov 2 , Ngiotensin Converting Enzyme 2 , Covid 19 , Ibonucleic Acid , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

In a new study, researchers reported severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein and S messenger ribonucleic acid (mRNA) nuclear co-translocation as a novel feature of SARS-CoV-2 pathogenesis. ....

United States , Middle East , Cov Urbani , Coronavirus Disease Covid 19 , Ibonucleic Acid , Ars Cov 2 , Spike Protein , Ngiotensin Converting Enzyme 2 , Covid 19 , N Vitro , Ers Cov , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,