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USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons. ....

Giorgia Quadrato , Sandeep Paul , Neil Tedeschi , Ranmal Samarasinghe , Edward Mallinckdot Jr , Carlos Lois , Marcelop Coba , Anoothi Seth , Alexander Atamian , Ryan Taylor , Macella Birtele , Tuan Nguyen , R Wright Foundation , Stem Cell Research , Keck School Of Medicine , Edythe Broad Foundation , Quadrato Lab , California Institute Of Technology , Cell Stem , Edythe Broad , Regenerative Medicine , Keck School , Negar Hosseini , Ashley Del Dosso , Spatial Genomics , California Institute ,

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease
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Sandeep Paul , Carlos Lois , Tuan Nguyen , Ryan Taylor , Anoothi Seth , Ranmal Samarasinghe , Alexander Atamian , Neil Tedeschi , Marcelop Coba , Giorgia Quadrato , Macella Birtele , Stem Cell Research , Keck School Of Medicine , Quadrato Lab , California Institute Of Technology , Cell Stem , Edythe Broad , Regenerative Medicine , Keck School , Negar Hosseini , Ashley Del Dosso , Spatial Genomics , California Institute ,