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USC Scientists Use Stem Cells to study human cerebellar development and disease

Stem cell research is controversial because of its association with abortion, but such research has become essential to understanding the human body and developing new ways to treat disease. Scientists at the University of Southern California (USC) Keck School of Medicine say they have used stem cells to develop a “game-changing” organoid model to study […]

Brain Organoids : Lab-Grown Cell Clusters Model Brain Functions

Scientists can coax stem cells into clusters that mimic the functions of brain regions, which could help us understand brain disorders.

Neural Organoid Models Cerebellum Development and Disorders

Neural Organoid Models Cerebellum Development and Disorders
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Scientists develop game-changing organoid model to study human brain development

Scientists develop game-changing organoid model to study human brain development
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USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

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