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Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived. ....

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UPMC: Reinvigorating 'Lost Cause' Exhausted T Cells Could Improve Cancer Immunotherapy | India Education | Latest Education News | Global Educational News

UPMC: Reinvigorating 'Lost Cause' Exhausted T Cells Could Improve Cancer Immunotherapy | India Education | Latest Education News | Global Educational News
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United States , San Diego , Ronal Peralta , Paolo Da Vignali , Nicolee Scharping , B Rhodes Ford , Amanda Poholek , Greg Delgoffe , Andrewt Frisch , Nataliel Rittenhouse , Konstantinos Lontos , University Of California , University Of North Carolina At Chapel Hill , University Of Pittsburgh , Health Sciences Sequencing Core , Pitt School Of Medicine , Hillman Cancer Center , Tumor Microenvironment Center , Science Immunology , North Carolina , Chapel Hill ,

Reinvigorating 'lost cause' exhausted T cells could improve cancer immunotherapy

Reinvigorating 'lost cause' exhausted T cells could improve cancer immunotherapy
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