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ACMG releases new Points to Consider statement on the clinical utility of polygenic risk scores for embryo selection

Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service. ....

Susan Klugman , Theresaa Grebe , American College Of Medical Genetics , Medical Genetics , Legal Issues Committee , American College , Polygenic Risk Scores , Embryo Selection , Consider Statement , Cardiovascular Disease , N Vitro , Public Health ,

"Laboratory testicles" could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis. ....

Cheli Lev , Aviya Stopel , Nitzan Gonen , International Journal Of Biological Sciences , Goodman Faculty Of Life Sciences , Institute Of Nanotechnology , Ilan University , Stav Dahari , Goodman Faculty , Life Sciences , Advanced Materials , Bar Ilan University , International Journal , N Vitro , Emale Infertility ,

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms. ....

Rudmer Zwerver , Leschenault Rousette Rousettus , Nature Communications , Search Tool , Transposase Accessible Chromatin , Gene Editing , N Vitro , N Vivo ,