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Measurement of mitochondrial toxicity using hepatocytes

Agilent Technologies describes the use of human primary hepatocytes in the context of the Agilent Seahorse XF Mito Tox ....

Agilent Technologies , Application Note , Agilent Seahorse , N Vitro ,

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital). ....

David Liu , Xianqun Fan Department Of Ophthalmology , Science China , Xianqun Fan , Shanghai Jiao Tong University School , Medicine Affiliated Ninth People , Genome Editing , N Vitro , Reverse Transcriptase ,

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research. ....

Nature Reviews Drug Discovery , Covid 19 , Drug Discovery , N Vitro , Protein Synthesis ,