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Do preservative and stray proteins cause rare COVID-19 vaccine side effect?


Science’s COVID-19 reporting is supported by the Heising-Simons Foundation.
Researchers in Germany and Canada have added provocative new details to their proposal for how the COVID-19 vaccine made by AstraZeneca might be causing an unusual clotting disorder in a small number of recipients. The mechanism, involving stray human proteins and a preservative in the vaccine, remains speculative. And it is not clear whether their hypothesis explains similar reactions observed in recipients of the COVID-19 vaccine made by Johnson & Johnson (J&J).
The new data are “interesting but not a smoking gun by any means” for the group’s hypothesis, says Gowthami Arepally, a hematologist at the Duke University School of Medicine who is working as an external consultant with AstraZeneca on the issue. But figuring out what in a COVID-19 vaccine might start the sometimes fatal combination of blood clotting and low platelets is crucial for developing better treatments for the side effe ....

Mecklenburg Vorpommern , United States , Rolf Marschalek , Emer Cooke , Yu Xuefeng , Gowthami Arepally , Mortimer Poncz , Kai Kupferschmidt , Paul Offit , Andreas Greinacher , Gretchen Vogel , Cansino Biologics , Heising Simons Foundation , Duke University School Of Medicine , Goethe University Frankfurt , Russian Gamaleya National Research Institute Of Epidemiology , University Of Greifswald , Research Square , Gamaleya Institute , European Medicines Agency , Duke University School , Science Insider , Russian Gamaleya National Research Institute , மெக்லென்பர்க் வோர்பொம்மேர்ன் , ஒன்றுபட்டது மாநிலங்களில் , எமர் சமைக்க ,