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Cross-protection from seasonal epidemics of human coronaviruses (HCoVs) has been hypothesized to contribute to the relative sparing of children during the early phase of the pandemic. Testing this relies on understanding the prepandemic age distribution of recent HCoV infections, but little is known about their dynamics. Using England and Wales as a case study, we use a transmission model to estimate the duration of immunity to seasonal coronaviruses, and show how cross-protection could have affected the age distribution of susceptibility during the first wave, and could alter SARS-CoV-2 transmission patterns over the coming decade.
The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia science.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from science.org Daily Mail and Mail on Sunday newspapers.
Acknowledgments: We thank all health care workers, Slovak armed forces, and countless volunteers who helped with the execution of the mass testing campaign. Further, we thank all participants who contributed their time to help curb the pandemic and particularly those who had to quarantine as a result of their or their household’s or contact’s test result.
Funding: This work was supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society 208812/Z/17/Z (to S.Fl.); Wellcome Trust Senior Research Fellowship (to S.Fu., S.A., and K.S.); and Elrha’s Research for Health in Humanitarian Crises (R2HC) Programme funded by the UK Government (DFID), the Wellcome Trust, and the UK National Institute for Health Research (NIHR) (K.V.-Z.). The following funding sources are acknowledged as providing funding for the working group authors: BBSRC LIDP BB/M009513/1 (to D.S.); Bill & Melinda Gates Foundation INV-001754 (to M.Q.); INV-003174 (to K.P., M.J., an
The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.