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Long-term vaccination strategies to mitigate the impact of SARS-CoV-2 transmission: A modelling study

In a modelling study, Alexandra Hogan and colleagues investigate long term vaccination strategies to mitigate the impact of SARS-CoV-2 transmission. ....

United Kingdom , United States , Mirjamee Kretzschmar , Sarah Pallas , Nick Grassly , Olivera Mesa , World Health , World Health Organisation , United Kingdom Medical Research Council , Commonwealth Development Office , Wales Ministry Of Health , Imperial College Research Fellowship , British Society For Immunology Covid , European Union , Community Jameel , United Kingdom Vaccines Network , Pfizer Inc , Health Economics , Health Protection Unit For , Melinda Gates Foundation , Drug Administration , Centre For Global Infectious Disease Analysis , World Health Organization , Coronavirus Disease , Severe Acute Respiratory Syndrome Coronavirus , Acute Respiratory Syndrome Coronavirus ,

Association of pneumococcal carriage in infants with the risk of carriage among their contacts in Nha Trang, Vietnam: A nested cross-sectional survey

Author summary Why was this study done? There is little information in the current literature on pneumococcal transmission to infants. Since individuals in this age group are at major risk of pneumococcal disease and at potentially reduced protection in reduced dose pneumococcal vaccination schedules, we carried out a study to identify their close contacts and likely routes of transmission. What did the researchers do and find? We identified all 7,428 physical contacts of 1,583 infants in Nha Trang, a coastal city in Vietnam. We found that there was a high correlation between infant infection and their probability of contact with at least 1 pneumococcal carrier on the surveyed day. Preschool-age children contributed around half of the total direct pneumococcal exposure risk to infants in Nha Trang. Around 80% of the exposure risk came from contact with household members. What do these findings mean? Social contact surveys can help to identify possible transmission pathways. I ....

United Kingdom , Nha Trang , Khá Hòm , Republic Of , Khanh Hoa , An Giang , Han I , Minh Xuan Bui , Kim Mulholland , Mirjamee Kretzschmar , Jason Hinds , Taqman Geneexpression Mastermix , Royal Society Grant , London School Of Hygiene Tropical Medicine , Pasteur Institute In Nha Trang , Merck Investigator Studies Program , Pasteur Institute Of Nha Trang , Khanh Hoa Health , World Health Organization , Khanh Hoa Health Service , Melinda Gates Foundation Grant , Career Development Fellowship , Murdoch Children Research Institute , National Institute Of Hygiene , Victorian Government Operational Infrastructure Support Program , Universitair Medisch Centrum Utrecht ,

Introduction and expansion of the SARS-CoV-2 B.1.1.7 variant and reinfections in Qatar: A nationally representative cohort study

Laith Abu-Raddad and colleagues describe the introduction and expansion of the SARS-CoV-2 B.1.1.7 variant in a national cohort in Qatar. ....

United Kingdom , Mirjamee Kretzschmar , Qatar Genome Programme , Qatar Ministry Of Public Health , Gilead Sciences , Hamad Medical Corporation , Public Health , Ministry Of Public Health , Health Care Corporation , Biomedical Research Program , Biomathematics Research Core , Universitair Medisch Centrum Utrecht , Creative Commons Attribution License , Qatar Ministry , Her Excellency , Weill Cornell Medicine Qatar , Genomics Core , Weill Cornell Medicine , Primary Health Care Corporation , Qatar Biobank , Sidra Medicine , Sars Cov 2 , Virus Testing , Respiratory Infections , Medical Risk Factors , Infectious Disease Epidemiology ,

Vaccine effectiveness against SARS-CoV-2 infection, hospitalization, and death when combining a first dose ChAdOx1 vaccine with a subsequent mRNA vaccine in Denmark: A nationwide population-based cohort study

Mie Agermose Gram and co-workers study the effectiveness of heterologous SARS-CoV-2 vaccine combinations in the Danish population. ....

Netherlands General , United Kingdom , Oxford Astrazeneca , Mirjamee Kretzschmar , Danish Data Protection Agency , Danish Health Data Authority , Danish Health Authority , International Classification Of Diseases , Danish National Patient Registry , Department Of Data Integration , R Foundation For Statistical Computing , Coronavirus Disease , Severe Acute Respiratory Syndrome Coronavirus , Danish Civil Registration , Universitair Medisch Centrum Utrecht , Creative Commons Attribution License , Civil Registration System , International Classification , Danish Civil Registration System , Danish Vaccination Registry , Observational Routinely Collected , Danish Microbiology Database , Statistical Computing , Data Integration , Statens Serum Institut , Viral Vaccines ,

Transmission of community- and hospital-acquired SARS-CoV-2 in hospital settings in the UK: A cohort study

In a cohort study, Mo Yin and colleagues investigate transmission of community- and hospital-acquired SARS-CoV-2 in hospital settings in the UK. ....

United Kingdom , Monte Carlo , Mirjamee Kretzschmar , Confidentiality Advisory Group , Infections In Oxfordshire Research Database , Mahidol Oxford Tropical Medicine Research Unit , Oxford University Hospitals , Department Of Health , European Union , Research Council , Zoonotic Infections At University Of Liverpool , Research Ethics Committee , United Kingdom National Health Service , Department Of Health Or Public England , University Of Oxford , Wellcome Trust Clinical Career Development , Health Research Authority , National Institute For Health Research , Antimicrobial Resistance At Oxford University , Biomedical Research Centre , Centre For Global Infectious Disease Analysis , Singapore National Medical Research Council Fellowship , Liverpool School Of Tropical Medicine , Commonwealth Development Office , Severe Acute Respiratory Syndrome Coronavirus , Coronavirus Disease ,