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Drugs targeting FXR1 may treat vascular proliferative diseases

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021). ....

United States , Michaelv Autieri , Emily Henderson , World Health Organization , Department Of Cardiovascular Sciences , American Journal , Lead Investigator , Cardiovascular Sciences , Lewis Katz School , Temple University , Cell Cycle , Myocardial Infarction , Renal Failure , Ascular Smooth Muscle Cell ,

Study identifies a new potential target for treating vascular disease

Study identifies a new potential target for treating vascular disease
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United States , Sherie Kelemen , Amandam Peluzzo , Michaelv Autieri , Satoru Eguchi , Rachaeln Okune , Dales Haines , Tani Leigh , Department Of Cardiovascular Sciences , World Health Organization , American Society For Investigative Pathology , National Heart , Elsevier Foundation , Blood Institute , American Journal , Cardiovascular Sciences , Lewis Katz School , Temple University , Intimal Hyperplasia , Induces Senescence , Vascular Smooth Muscle Cells , American Society , Investigative Pathology , Diversity Advisory Board , Press Release Image , Fragile X ,

Study identifies a new potential target for t

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021). Vascular smooth muscle cell (VSMC) activation plays a crucial role in the development of multiple vascular diseases. In a novel study in The American Journal of Pathology, published by Elsevier, researchers found that when fragile-X related protein-1 (FXR1) is absent, VSMC proliferate more slowly, become senescent, and scar tissue (neointima) development is reduced. Therefore, drugs targeting FXR1 may treat vascular proliferative diseases. ....

United States , Michaelv Autieri , World Health Organization , Method Of Research , Department Of Cardiovascular Sciences , American Journal , Cardiovascular Sciences , Lewis Katz School , Temple University , Intimal Hyperplasia , Induces Senescence , Vascular Smooth Muscle ,

New Study Reveals Potential Target for Treating Vascular Disease

New Study Reveals Potential Target for Treating Vascular Disease
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United States , Michaelv Autieri , Department Of Cardiovascular Sciences , World Health Organization , American Journal , Cardiovascular Sciences , Lewis Katz School , Temple University ,

Researchers discover new potential target for treating vascular disease

Vascular disorders, which include myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one-third of all deaths in the United States, Europe, and developing countries (World Health Organisation, 2021). The activation of vascular smooth muscle cells (VSMCs) is critical in the development of a variety of vascular disorders. ....

United States , Michaelv Autieri , World Health Organisation , Department Of Cardiovascular Sciences , American Journal , Cardiovascular Sciences , Lewis Katz School , Temple University , Vascular Diseases , Cell Proliferation , Vascular Smooth Muscle Cells , Na Binding Proteins , Cardiovascular Disease , Muscle Damage ,