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Evolution: Miniproteins appeared "from nowhere"

Evolution: Miniproteins appeared "from nowhere"
scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.

Max Delbr , Jorge Ruiz Orera , Jana Schulz , Van Heesch , Clara Sandmann , Michael Gotthardt , Philipp Mertins , Sebastiaan Van Heesch , Cardiovascular Research , Berlin Institute Of Health At Charit , German Center , Pediatric Oncology , Molecular Cell , Proteomics Platform , Berlin Institute , Professors Michael Gotthardt , Thomas Willnow ,

MDC Receives ERC Advanced Grant for Cardiac Research

This ERC Advanced Grant is awarded to scientists with more than ten years of research experience who have already played a prominent role in their field. ....

Max Delbr , Michael Gotthardt , Helmholtz Association , European Research Council , Cardiovascular Cell Biology , Molecular Medicine , Advanced Grant ,

Softening a Hardened Heart Counts on Cardiac Splicing Regulators

Scientists have developed a therapeutic agent to treat heart failure caused by the stiffening of the walls of the chambers of the heart that prevents adequate filling of the chambers even when the pumping activity of the heart is normal. This form of heart failure has no available treatment at present. The authors have targeted a splicing factor that regulates the splicing of titin, a protein that regulates the elasticity of the heart walls. ....

United States , Baden Wüberg , Max Delbr , Michael Gotthardt , Victor Badillo Lisakowski , Michael Radke , Helmholtz Association , Ionis Pharmaceuticals , Heidelberg University , Molecular Medicine , Science Translational Medicine , Badillo Lisakowski ,

Location of receptors is decisive

Location of receptors is decisive
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Baden Wüberg , Max Delbr , Martin Lohse , Peter Gmeiner , Philipp Gmach , Horst Holger Boltz , Michael Gotthardt , Martinj Lohse , Paolo Annibale , Bioscience Institute , Institute Of Pharmacology , Munich Planegg , National Academy , United States , Pharmaceutical Chemistry , Marc Bathe Peters , Sciences United States , மார்டின் லோசெ , பீட்டர் கிமேனேற் , உயிர் அறிவியல் நிறுவனம் , நிறுவனம் ஆஃப் மருந்தியல் , தேசிய கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் , மருந்து வேதியியல் , அறிவியல் ஒன்றுபட்டது மாநிலங்களில் ,

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project
Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.
Despite advances in prevention and therapy, cardiovascular diseases are still one of the leading causes of death worldwide. Scientists have only recently begun to understand the key role of alternative splicing - the stitching together of messenger RNA during gene transcription - in cardiovascular diseases. The Leducq Foundation is providing 7 million U.S. dollars over the next five years to support the Cardiac Splicing as a Therapeutic Target (CASTT) project, which is comprised of six E ....

United States , France General , Max Delbr , Emily Henderson , Jean Leducq , Benjamin Meder , Maria Carmo Fonseca , Michael Gotthardt , Leslie Leinwand , Lars Steinmetz , Euan Ashley , University Of Lisbon , Helmholtz Association , University Of Colorado Boulder , Biofrontiers Institute At University Of Colorado Boulder , Leducq Foundation , Stanford University , Heidelberg University Hospital , Professor Leslie Leinwand , Colorado Boulder , Cardiac Splicing , Therapeutic Target , Molecular Medicine , North American Coordinator , Professor Euan Ashley , Professor Maria Carmo Fonseca ,