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Aptorum Group Limited: Aptorum Group Announces Completion of Pre-IND Discussions with US FDA on its ALS-4, a First-in-Class Small Molecule Drug Targeting Methicillin Resistant Staphylococcus Aureus

Regulatory News: Aptorum Group Limited (Nasdaq: APM, Euronext Paris: APM) ("Aptorum Group" or "Aptorum"), a clinical-stage biopharmaceutical company, announces the completion of the Pre-IND discussions ....

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MRSA: Bacteria on hedgehogs evolved antibiotic resistance before use of drugs

A strain of the antibiotic-resistant bacterium MRSA seems to have colonised the skin of hedgehogs more than 200 years ago – and many other similarly evasive bugs might exist in nature ....

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Rocketing to No. 6 internationally, No. 1 in Big Ten: Purdue among world leaders in patents

175 utility patents on Purdue inventions issued in 2020 WEST LAFAYETTE, Ind. The whitest of white paints that could significantly reduce the cost. ....

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Tree resin could cure infections caused by MRSA bacteria

Date Time
Tree resin could cure infections caused by MRSA bacteria
Currently, MRSA is one of the fastest evolving bacteria, causing a wide range of infections from skin disease to serious endocarditis. Researchers at the University of Helsinki created a new biopolymer which kills MRSA nearly 100% upon contact, by combining nanocellulose with compounds derived from tree resin, a side stream from forest industry.
Methicillin-resistant S. aureus (MRSA) is any strain of S. aureus that has developed resistance towards the broad-spectrum β-lactam antibiotics such as cloxacillin, methicillin and flucloxacillin. Various sequelae can result from MRSA infection such as chronic wound infection, sepsis or ventilator-associated pneumonia. MRSA is the leading cause of chronic infections associated to the use of indwelling medical devices. ....

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Aptorum Group Limited: Aptorum Group Receives Clearance from Health Canada to Initiate a Phase 1 Clinical Trial for ALS-4, a Small Molecule Drug for Infections Caused by Staphylococcus aureus including Methicillin-resistant Staphylococcus aureus (MRSA)

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Aptorum Group Limited (Nasdaq: APM, Euronext Paris: APM) ( Aptorum Group or Aptorum ), a biopharmaceutical company focused on novel technologies including the targeting of infectious diseases, announced that the company, through its wholly owned subsidiary, Aptorum International Limited, has received clearance from the Public Health Agency of Canada (Health Canada) regarding the Clinical Trial Application (CTA) to commence a Phase 1 study of ALS-4, an orally administered small molecule drug intended to treat infections caused by
Staphylococcus aureus including MRSA.
Dr. Clark Cheng, Chief Medical Officer and Executive Director of Aptorum Group, commented, The clearance of our CTA application for ALS-4 drug represents a significant milestone for the company and one of a number of targeted strategic goals for 2021. This milestone supports the transition of Aptorum Group to a clinical-stage company and reflects the potential of our scientific rigor and novel appr ....

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