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First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib

MELBOURNE, Australia, July 19, 2023 /PRNewswire/ Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company)today announces that the first patient has been dosed in a Phase I study of the Company's investigational targeted radiation therapy, TLX250, in combination with a Merck KGaA, Darmstadt, Germany (Merck) DNA-dependent protein kinase (DNA-PK) inhibitor candidate, peposertib (M3814). The study is being conducted in patients with solid tumours expressing carbonic-anhydrase IX (CAIX), a potential pan-cancer target. STARSTRUCK (ClinicalTrials.gov Identifier: NCT05868174) is a Phase Ib, open label, single-arm, multicentre dose escalation and dose expansion study to evaluate the safety profile, dosing and activity of TLX250 (177Lu-DOTA-girentuximab) in combination with the DNA damage response inhibitor (DDRi) peposertib, which is an inhibitor of DNA-PK. The target population is patients with CAIX-expressing solid tumours that are relapsed or refractory to standard therapies. Up to ....

United States , United Kingdom , Merck Ddri , Nat Lenzo , Kyahn Williamson , Colin Hayward , Genesiscare Murdoch , Health Canada , Telix Pharmaceuticals , Merck Kga , European Union , Merck Kgaa , Australian Therapeutic Goods Administration , Prnewswire Telix Pharmaceuticals Limited , Genesiscare Group Clinical , Drug Administration , Australian Securities Exchange , Corporate Communications , Pharmaceuticals Limited , Professor Nat Lenzo , Genesiscare Group Clinical Director Theranostics , Chief Medical Officer , Telix Pharmaceuticals Limited , July 19 , 023 Prnewswire Telix Pharmaceuticals Limited Asx Tlx , He Company Today Announces That The First Patient Has Been Dosed Ina Phasei Study Of 39s Investigational Targeted Radiation Therapy ,

Telix Pharmaceuticals Limited: First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib

Telix Pharmaceuticals Limited: First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib
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United Kingdom , United States , Genesiscare Murdoch , Nat Lenzo , Colin Hayward , Merck Ddri , Kyahn Williamson , European Union , Australian Securities Exchange , Australian Therapeutic Goods Administration , Telix Pharmaceuticals , Genesiscare Group Clinical , Health Canada , Corporate Communications , Merck Kgaa , Merck Kga , Drug Administration , Prnewswire Telix Pharmaceuticals Limited , Pharmaceuticals Limited , Professor Nat Lenzo , Genesiscare Group Clinical Director Theranostics , Chief Medical Officer , Telix Pharmaceuticals Limited , Die Experten ,

First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib

First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib
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United Kingdom , United States , Merck Ddri , Nat Lenzo , Genesiscare Murdoch , Kyahn Williamson , Colin Hayward , Genesiscare Group Clinical , Merck Kgaa , Australian Therapeutic Goods Administration , Merck Kga , Drug Administration , Health Canada , Telix Pharmaceuticals , Australian Securities Exchange , European Union , Corporate Communications , Prnewswire Telix Pharmaceuticals Limited , Pharmaceuticals Limited , Professor Nat Lenzo , Genesiscare Group Clinical Director Theranostics , Chief Medical Officer , Telix Pharmaceuticals Limited ,

First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib

/PRNewswire/ Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company) today announces that the first patient has been dosed in a Phase I study of the. ....

United States , United Kingdom , Merck Ddri , Nat Lenzo , Colin Hayward , Genesiscare Murdoch , Kyahn Williamson , Merck Kga , Corporate Communications , Prnewswire Telix Pharmaceuticals Limited , Merck Kgaa , Australian Securities Exchange , Drug Administration , Australian Therapeutic Goods Administration , Telix Pharmaceuticals , Genesiscare Group Clinical , Health Canada , European Union , Pharmaceuticals Limited , Professor Nat Lenzo , Genesiscare Group Clinical Director Theranostics , Chief Medical Officer , Telix Pharmaceuticals Limited ,

First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib

First Patient Dosed in STARSTRUCK Study of TLX250 Targeted Radiation Therapy in Combination with Merck Investigational DNA-PK Inhibitor, Peposertib
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