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Cellular traffic controllers caught managing flow of signals from receptors: First time that individual beta-arrestin molecules are directly observed as they control receptor-mediated signals in living cells using advanced microscopy

Cellular traffic controllers caught managing flow of signals from receptors: First time that individual beta-arrestin molecules are directly observed as they control receptor-mediated signals in living cells using advanced microscopy
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Yann Lanoisel , Zsombor Koszegi , Davide Calebiro , Institute Of Metabolism , Research Council , University Of Birmingham , Wellcome Trust India Alliance , Centre Of Membrane , Systems Research , Professor Davide Calebiro , Molecular Endocrinology , Membrane Proteins , Prof Calebiro , Wellcome Trust , Medical Research Council , Wellcome Trust India ,

Relatives discovered: Membrane proteins of cy

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks. The cell membrane encloses the cell interior, but is constantly remodeled, for example, due to membrane budding, invagination, or fusion processes. This also involves various proteins that were long assumed to be present exclusively or predominantly in higher organisms. In the past 10 to 20 years, however, proteins have been identified or predicted to be present also in simple organisms that do not possess a nucleus. In a research collaboration, a protein involved in membrane remodeling in cyanobacteria has now been described for the first time. The existence of such a bacterial protein was suspected, but proof was still pending. The studied protein is likely a bacterial representative of a similar protein found in higher organisms such as animals and plants. ....

Lucas Gewehr , Carsten Sachse , Dirk Schneider , Max Planck Graduate Center , Nature Communications , Heinrich Heine University , Johannes Gutenberg University Mainz , Aarhus University , Mainz University , Professor Dirk Schneider , Membrane Proteins , Professor Carsten Sachse , Professor Dirk , Ruven Jilly , Benedikt Junglas , Max Planck Institute , Polymer Research , Bioscience Reports ,

Membrane Proteins of Cyanobacteria and Higher Organisms Share High Structural Similarity in Newly Discovered Relatives

Membrane Proteins of Cyanobacteria and Higher Organisms Share High Structural Similarity in Newly Discovered Relatives
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Carsten Sachse , Dirk Schneider , Lucas Gewehr , Nature Communications , Mainz University , Heinrich Heine University , Johannes Gutenberg University Mainz , Max Planck Graduate Center , Aarhus University , Professor Dirk Schneider , Membrane Proteins , Professor Carsten Sachse , Professor Dirk , Ruven Jilly , Benedikt Junglas , Max Planck Institute , Polymer Research ,

Quantifying & characterizing membrane protein interactions

Infographic: A 4-step workflow for purification-free affinity and concentration measurement of membrane-protein targets ....

Fluidity One M , Membrane Proteins , Protein Interactions , Microfluidic Diffusional Sizing ,

GABA Action Relies on Protein 'Anchors'

GABA Action Relies on Protein 'Anchors'
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Davide Calebiro , Nature Communications , University Of Nottingham , Centre Of Membrane , University Of Birmingham , Molecular Endocrinology , Membrane Proteins ,