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Cellular Controllers Captured in Action

A team of international researchers led by Professor Davide Calebiro from the University of Birmingham, have used advanced microscopy to understand the role of beta-arrestin molecules in controlling activity of G protein-coupled receptors (GPCRs) the largest group of receptors in the human body. Click to read more. ....

United Kingdom , Davide Calebiro , Zsombor Koszegi , Yann Lanoisel , Centre Of Membrane , Systems Research , Research Council , University Of Birmingham , Institute Of Metabolism , Wellcome Trust India Alliance , Professor Davide Calebiro , Molecular Endocrinology , Membrane Proteins , Prof Calebiro , Wellcome Trust , Medical Research Council , Wellcome Trust India ,

Cellular traffic controllers caught managing

Proteins that act like air traffic controllers, managing the flow of signals in and out of human cells, have been observed for the first time with unprecedented detail using advanced microscopy techniques.

New findings published in Cell could inform the development of better drugs for pain relief, diabetes or heart failure ....

Zsombor Koszegi , Davide Calebiro , Yann Lanoisel , Wellcome Trust India Alliance , Institute Of Metabolism , Systems Research , Centre Of Membrane , University Of Birmingham , Method Of Research , Research Council , Professor Davide Calebiro , Molecular Endocrinology , Membrane Proteins , Prof Calebiro , Wellcome Trust , Medical Research Council , Wellcome Trust India ,

Cellular traffic controllers caught managing flow of signals from receptors: First time that individual beta-arrestin molecules are directly observed as they control receptor-mediated signals in living cells using advanced microscopy

Cellular traffic controllers caught managing flow of signals from receptors: First time that individual beta-arrestin molecules are directly observed as they control receptor-mediated signals in living cells using advanced microscopy
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Yann Lanoisel , Zsombor Koszegi , Davide Calebiro , Institute Of Metabolism , Research Council , University Of Birmingham , Wellcome Trust India Alliance , Centre Of Membrane , Systems Research , Professor Davide Calebiro , Molecular Endocrinology , Membrane Proteins , Prof Calebiro , Wellcome Trust , Medical Research Council , Wellcome Trust India ,