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In COPD and Pulmonary Hypertension, Potential Care Gaps Warrant Further Research

Intravenous ravulizumab in mechanically ventilated patients hospitalised with severe COVID-19: a phase 3, multicentre, open-label, randomised controlled trial

Addition of ravulizumab to BSC did not improve survival or other secondary outcomes. Safety findings were consistent with the known safety profile of ravulizumab in its approved indications. Despite the lack of efficacy, the study adds value for future research into complement therapeutics in critical illnesses by showing that C5 inhibition can be accomplished in severely ill patients.

The long-term impact of COVID-19 severity on health-related quality of life

A recent study conducted on the residents of Amsterdam, the Netherlands, describes that people with mild COVID-19 experience better health-related quality of life after one year of disease onset than those with moderate or severe COVID-19.

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