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As Time Goes By, Post-TAVI Thrombus Becomes More OAC Resistant

HALT on imaging might be most responsive to treatment if detected within the first year of implantation, say researchers. ....

New York , United States , Rebecca Hahn , Aloke Finn , Los Angeles , Raj Makkar , Michael Young , Ryu Sato , Md University Of Maryland Medical Center , Sinai Medical Center , Hitchcock Medical Center , Md Cvpath Institute , Cvpath Institute , Presbyterian Columbia University Irving Medical Center , Maryland Medical Center , Just Getting , Columbia University Irving Medical Center , Cedars Sinai Medical Center , Dartmouth Hitchcock Medical Center ,

Embolic Protection Snags Debris in Nearly All Lower-Risk TAVI Patients

The field awaits the results of PROTECTED TAVR to see whether the trial can deliver proof that the device reduces stroke risk. ....

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Microvascular Thrombi Common in Patients Dying of COVID-19

January 27, 2021
Two new pathology studies are highlighting the prevalence of microvascular thrombi in the hearts of patients with COVID-19 and exploring the role they might play in causing acute ischemic injury.
In the first, which was led by Giulio Guagliumi, MD (Ospedale Papa Giovanni XXIII, Bergamo, Italy), and senior investigator Aloke Finn, MD (CVPath Institute, Gaithersburg, MD), more than one-third of patients who died of COVID-19 had evidence of cardiac injury, predominantly focal myocyte necrosis, the cause of which they attribute to microthrombi present in the myocardial capillaries, arterioles, and small muscular arteries.
More of TCTMD s coverage on our COVID-19 hub. ....

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True Myocarditis Uncommon in COVID-19, Review Concludes

January 20, 2021
Among patients with COVID-19, the incidence of myocarditis is less than 5%, according to a review paper that looked at evidence from tissue taken either at autopsy or endomyocardial biopsy.
Coronavirus-related myocarditis has been a topic of concern over the last year, beginning with small postmortem reports from Wuhan, China, of fulminant myocarditis in some patients, followed by publication of a controversial cardiac magnetic resonance (CMR) study suggesting that more than three-quarters of middle-age adults some with mild or no symptoms had ongoing cardiac involvement weeks or even months after recovering from COVID-19. There also was some evidence even among young adults, with a small analysis of 26 college competitive athletes who’d tested positive for the virus showing that four had CMR imaging evidence of myocarditis and eight had signs of prior myocardial injury. ....

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