January 27, 2021 Two new pathology studies are highlighting the prevalence of microvascular thrombi in the hearts of patients with COVID-19 and exploring the role they might play in causing acute ischemic injury. In the first, which was led by Giulio Guagliumi, MD (Ospedale Papa Giovanni XXIII, Bergamo, Italy), and senior investigator Aloke Finn, MD (CVPath Institute, Gaithersburg, MD), more than one-third of patients who died of COVID-19 had evidence of cardiac injury, predominantly focal myocyte necrosis, the cause of which they attribute to microthrombi present in the myocardial capillaries, arterioles, and small muscular arteries. More of TCTMD's coverage on our COVID-19 hub.