Freiburg surgeons develop new treatment method to improve survival after cardiac arrest
Around 50,000 people suffer sudden cardiac arrest in Germany every year. When occurring outside a hospital, the chances of survival are only ten percent. Survivors often suffer from severe permanent neurological damage. On July 21st, 2021, researchers from the Faculty of Medicine - University of Freiburg, Germany, published together with German and US colleagues a review article in the journal
Nature Reviews Neuroscience. They describe the most important therapeutic factors for successful resuscitation.
The scientists name the therapy concept based on these factors CARL (Controlled Automated Reperfusion of the whole body). In recent years, the Freiburg physicians and perfusionists have already developed a special and mobile heart-lung machine for resuscitation that allows CARL therapy for the first time. One of the first persons treated with CARL therapy successfully survived a cardiac arrest
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Credit: MPI for Metabolism Research/ Nasim Biglari
The nerve cells, also called neurons, in our brain control all the basic processes of our body. For this reason, there are different types of neurons distributed over specific regions of the brain. Researchers at the Max Planck Institute for Metabolic Research and the CECAD Cluster of Excellence in Aging Research of the University of Cologne have developed an approach that allows them to show that neurons that are supposedly the same are actually very different: they not only sense different hormones for the body s energy state, but also have a different influence on food intake. This can have a direct effect on our metabolism, for example by differentially restraining our appetite.