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December 10, 2020 Patients who receive red blood cell transfusions after TAVR fare worse in the first 30 days compared with others, results from the TRITAVI registry show. In a propensity-matched analysis, transfusion was associated with about double the risk of early mortality (6.4% vs 3.1%), as well as greater risks of cerebrovascular accident and stage 2 or 3 acute kidney injury, according to researchers led by Marco Zimarino, MD, PhD (“SS. Annunziata” Hospital – Chieti, Italy). Transfusion was independently associated with 30-day mortality on multivariable analysis, along with major vascular complications and major bleeding, they report in a study published recently online in Circulation: Cardiovascular Interventions. “Physicians should refrain from liberal transfusion to patients. They should refrain from using red blood cell transfusion as a fluid repletion means or to correct a lower-than-expected hemoglobin value,” Zimarino told TCMTD, adding that these result

Francesco costaMarco zimarinoMauricio cohenPhd university of messinaMd university of miamiVon willebrandபிரான்செஸ்கோ கோஸ்டாம ur ரிசியோ கோஹன்ஃப்ட் பல்கலைக்கழகம் ஆஃப் மெசினாம்ட் பல்கலைக்கழகம் ஆஃப் மியாமி