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Most Older Adults with Primary Hyperparathyroidism Don't Undergo Parathyroidectomy


Jan 11, 2021
Consensus guideline recommendations have little effect on treatment decisions
Most older adults with primary hyperparathyroidism (PHPT) did not receive definitive treatment with parathyroidectomy, instead receiving non-operative management, researchers reported.
According to a population-based cohort study, older age, frailty, and multimorbidity had inverse associations with parathyroidectomy and guideline recommendations had minimal impact on treatment decisions, “especially among frail patients with a high comorbidity burden,” wrote Carolyn D. Seib, MD, MAS, Department of Surgery, Stanford University School of Medicine, Stanford, California, and colleagues in
PHPT is a common endocrine disorder that has tripled in prevalence over the past two decades, Seib and colleagues explained. It primarily affects older adults and is associated with an increased risk of osteoporotic fractures, nephrolithiasis, and chronic kidney disease, as well as neuroc ....

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Few Qualifying Medicare Patients Undergo Parathyroidectomy


Most older adults with primary hyperparathyroidism (PHPT) did not receive definitive parathyroidectomy, researchers reported.
In a retrospective analysis of over 210,000 Medicare beneficiaries, only 30% underwent this operation within a year of their initial diagnosis, reported Carolyn Dacey Seib, MD, of Stanford University School of Medicine in California, and colleagues.
Out of the 131,723 of these patients with PHPT who met consensus guidelines criteria for undergoing this operative management defined as diagnosis of osteoporosis, nephrolithiasis, or stage 3 chronic kidney disease (CKD) only 29.6% underwent a parathyroidectomy, they stated in
Parathyroidectomy is the only definitive treatment for PHPT, Seib s group wrote, adding that Evidence based criteria for the operative management of PHPT have expanded significantly since the first consensus guidelines were published in 1991. ....

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Martin Nilssons två aktietips för 2021 – "framtida vinnarna"

Martin Nilssons två aktietips för 2021 – "framtida vinnarna"
di.se - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from di.se Daily Mail and Mail on Sunday newspapers.

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Medieval Christmas | History Today


Medieval Christmas
Existing elements of pagan midwinter rites fused with the developing theology of Christmas in an appeal to the senses of both sacred and lay.
As the European winter deepens the course of the sun gets nearer the southern horizon until it seems to stand still for a few days, before slowly rising again to usher in the spring. Ancient peoples were of course aware of this phenomenon and the Romans, from their words for sun and stand still , called it solstitium, source of our word solstice . By the Julian calendar, the system of months and days we still use (first devised in 46 BC on orders from Julius Caesar), the winter solstice was originally dated December 25th. ....

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