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Estrogen status - not sex - protects against heightened fear recall


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Philadelphia, April 15, 2021 -A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner.
Aberrant fear-memory processing in the brain is thought to underlie anxiety disorders, which affect hundreds of millions of people worldwide. The neurobiological mechanisms underlying these disorders remain poorly understood, but recent studies suggest that neural oscillations in the prefrontal cortex can reflect the strength of fear recall activity, providing a physiological measure.
Women suffer from anxiety disorders at twice the rate of men and indeed the literature shows that there are sex differences in fear recall behaviors, but this area of study has not been extended to neural oscillations. Additional studies suggest a modulatory role for the female sex hormone estradiol (E2) for fear recall and extinction recall. ....

United States , Philipp Bierwirth , Martin Antov , Ursula Stockhorst , Rhiannon Bugno , Cameron Carter , Camerons Carter , Matthias Sperl , University Of California , University Of Osnabr , Society Of Biological Psychiatry , Elsevier Foundation , Editorial Office , Biological Psychiatry , Cognitive Neuroscience , Diversity Advisory Board , Medicine Health , ஒன்றுபட்டது மாநிலங்களில் , ரீயேநந் பக்னோ , கேமரூன் கார்ட்டர் , கேமரன்கள் கார்ட்டர் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , சமூகம் ஆஃப் உயிரியல் மனநல மருத்துவம் , தலையங்கம் அலுவலகம் , உயிரியல் மனநல மருத்துவம் , அறிவாற்றல் நரம்பியல் ,